Codeine and Toe swelling - a phase IV clinical study of FDA data
Summary:
Toe swelling is reported as a side effect among people who take Codeine (codeine sulfate), especially for people who are female, 40-49 old, have been taking the drug for 1 - 2 years also take Enbrel, and have Rheumatoid arthritis.
The phase IV clinical study analyzes which people have Toe swelling when taking Codeine. It is created by eHealthMe based on reports of 41,713 people who have side effects when taking Codeine from the FDA, and is updated regularly.
What is Codeine?
Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,341 Codeine users. Check the latest studies of Codeine.
What is Toe swelling?
Toe swelling is found to be associated with 3,080 drugs and 2,940 conditions by eHealthMe. Check the latest studies of Toe swelling.
41,713 people reported to have side effects when taking Codeine.
Among them, 3,038 people (7.28%) have Toe swelling.
Among these 3,038 people:
How long have people been on Codeine when they have Toe swelling? *
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 100 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Toe swelling when taking Codeine? *
- female: 96.24 %
- male: 3.76 %
What is the age of people who have Toe swelling when taking Codeine? *
- 0-1: 0.05 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.09 %
- 30-39: 5.02 %
- 40-49: 37.51 %
- 50-59: 26.82 %
- 60+: 30.52 %
What are other drugs people take besides Codeine? *
- Enbrel: 2,599 people, 85.55%
- Humira: 2,560 people, 84.27%
- Xeljanz: 2,300 people, 75.71%
- Orencia: 2,270 people, 74.72%
- Remicade: 2,254 people, 74.19%
- Actemra: 2,123 people, 69.88%
- Arava: 1,842 people, 60.63%
- Simponi: 1,618 people, 53.26%
- Cimzia: 1,526 people, 50.23%
- Prednisone: 1,479 people, 48.68%
What are other side effects people have besides Toe swelling? *
- Drug Ineffective: 2,431 people, 80.02%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2,250 people, 74.06%
- Rashes (redness): 2,165 people, 71.26%
- Drug Intolerance (drug sensitivity): 2,094 people, 68.93%
- Joint Pain: 2,016 people, 66.36%
- Infusion Related Reaction: 1,839 people, 60.53%
- Fatigue (feeling of tiredness): 1,771 people, 58.29%
- Drug Hypersensitivity: 1,709 people, 56.25%
- High Blood Pressure: 1,608 people, 52.93%
- Peripheral Swelling: 1,581 people, 52.04%
What are the existing conditions these people have? *
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2,597 people, 85.48%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 639 people, 21.03%
- Psoriasis (immune-mediated disease that affects the skin): 501 people, 16.49%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 286 people, 9.41%
- Herpes Zoster: 279 people, 9.18%
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 268 people, 8.82%
- Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 253 people, 8.33%
- Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 178 people, 5.86%
- Adenomatous Polyposis Coli ((fap) is an inherited condition in which numerous polyps form mainly in the epithelium of the large intestine): 165 people, 5.43%
- Ankylosing Spondylitis (type of arthritis affecting the spine): 141 people, 4.64%
* Approximation only. Some reports may have incomplete information.
Do you take Codeine and have Toe swelling?
- Check whether Toe swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Codeine:
- Codeine (42,341 reports)
Toe swelling treatments and more:
- Toe swelling (143,797 reports)
How severe was Toe swelling and when was it recovered:
Expand to all the drugs that have ingredients of codeine sulfate:
- Toe swelling and drugs with ingredients of codeine sulfate (1,653 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Common Codeine side effects:
- Codeine side effect: Drug hypersensitivity (11,243 reports)
- Codeine side effect: Rashes (redness) (4,891 reports)
- Codeine side effect: Nausea (feeling of having an urge to vomit) (4,385 reports)
Browse all side effects of Codeine:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon drugs associated with Toe swelling:
- Methotrexate side effect: Toe swelling (35,301 reports)
- Enbrel side effect: Toe swelling (33,115 reports)
- Humira side effect: Toe swelling (29,736 reports)
- Prednisone side effect: Toe swelling (25,150 reports)
- Orencia side effect: Toe swelling (23,926 reports)
- Actemra side effect: Toe swelling (20,911 reports)
- Xeljanz side effect: Toe swelling (19,622 reports)
- Sulfasalazine side effect: Toe swelling (17,311 reports)
- Leflunomide side effect: Toe swelling (16,071 reports)
- Arava side effect: Toe swelling (15,509 reports)
Browse all the drugs that are associated with Toe swelling:
- Toe swelling (3,080 drugs)
Common conditions associated with Toe swelling:
- Arthritis - rheumatoid: 55,223 reports
- Psoriatic arthropathy aggravated: 8,765 reports
- Hypertension aggravated: 6,211 reports
- Hbp: 6,190 reports
- Psoriasis: 5,582 reports
- Pain exacerbated: 5,382 reports
- Hypnosis and pain: 5,345 reports
- Rheumatoid spondylitis: 3,627 reports
- Granulomatous ileocolitis: 3,536 reports
- Multiple myeloma: 3,140 reports
Browse all the conditions that are associated with Toe swelling:
- Toe swelling (2,940 conditions)
Drugs similar to Codeine and Toe swelling :
- Acetaminophen side effect: Toe swelling
- Advil side effect: Toe swelling
- Aleve side effect: Toe swelling
- Amitriptyline hydrochloride side effect: Toe swelling
- Aspirin side effect: Toe swelling
- Celebrex side effect: Toe swelling
- Cymbalta side effect: Toe swelling
- Darvocet side effect: Toe swelling
- Darvocet-n 100 side effect: Toe swelling
- Dilaudid side effect: Toe swelling
- Flexeril side effect: Toe swelling
- Gabapentin side effect: Toe swelling
- Hydrocodone bitartrate and acetaminophen side effect: Toe swelling
- Hydromorphone hydrochloride side effect: Toe swelling
- Ibu side effect: Toe swelling
- Ibuprofen side effect: Toe swelling
- Lortab side effect: Toe swelling
- Lyrica side effect: Toe swelling
- Meloxicam side effect: Toe swelling
- Methadone hydrochloride side effect: Toe swelling
- Morphine side effect: Toe swelling
- Morphine sulfate side effect: Toe swelling
- Motrin side effect: Toe swelling
- Naproxen side effect: Toe swelling
- Neurontin side effect: Toe swelling
- Norco side effect: Toe swelling
- Oxycodone side effect: Toe swelling
- Oxycodone and acetaminophen side effect: Toe swelling
- Oxycodone hydrochloride side effect: Toe swelling
- Oxycontin side effect: Toe swelling
- Paracetamol side effect: Toe swelling
- Percocet side effect: Toe swelling
- Profen side effect: Toe swelling
- Suboxone side effect: Toe swelling
- Tramadol side effect: Toe swelling
- Tramadol hydrochloride side effect: Toe swelling
- Tylenol side effect: Toe swelling
- Tylenol w/ codeine side effect: Toe swelling
- Tylenol w/ codeine no. 3 side effect: Toe swelling
- Ultram side effect: Toe swelling
- Vicodin side effect: Toe swelling
- Vicodin es side effect: Toe swelling
How the study uses the data?
The study uses data from the FDA. It is based on codeine sulfate (the active ingredients of Codeine) and Codeine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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