Cogentin and Diabetic nephropathy - a phase IV clinical study of FDA data

Summary:

Diabetic nephropathy is reported as a side effect among people who take Cogentin (benztropine mesylate), especially for people who are female, 40-49 old, also take Seroquel, and have Bipolar disorder.

The phase IV clinical study analyzes which people have Diabetic nephropathy when taking Cogentin. It is created by eHealthMe based on reports of 7,418 people who have side effects when taking Cogentin from the FDA, and is updated regularly.

What is Cogentin?

Cogentin has active ingredients of benztropine mesylate. It is often used in tardive dyskinesia. eHealthMe is studying from 7,692 Cogentin users. Check the latest studies of Cogentin.

What is Diabetic nephropathy?

Diabetic nephropathy (diabetic kidney disease) is found to be associated with 437 drugs and 603 conditions by eHealthMe. Check the latest studies of Diabetic nephropathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

7,418 people reported to have side effects when taking Cogentin.
Among them, 13 people (0.18%) have Diabetic nephropathy.

Could Cogentin cause Diabetic nephropathy?

Among these 13 people:

What is the gender of people who have Diabetic nephropathy when taking Cogentin? *

female: 84.62 %
male: 15.38 %

What is the age of people who have Diabetic nephropathy when taking Cogentin? *

What are other drugs people take besides Cogentin? *

What are other side effects people have besides Diabetic nephropathy? *

Diabetic Ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 8 people, 61.54%
Diabetes: 8 people, 61.54%
Acute Kidney Failure: 7 people, 53.85%
Type 2 Diabetes: 7 people, 53.85%
Pancreatitis (inflammation of pancreas): 5 people, 38.46%
Neuropathy Peripheral (surface nerve damage): 5 people, 38.46%
Altered State Of Consciousness (altered state of mind): 4 people, 30.77%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 4 people, 30.77%
Loss Of Consciousness: 4 people, 30.77%
Hypoglycemia (low blood sugar): 4 people, 30.77%

What are the existing conditions these people have? *

Depression: 5 people, 38.46%
Bipolar Disorder (mood disorder): 5 people, 38.46%
Hallucinations (sensations that appear real but are created by your mind): 2 people, 15.38%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 1 person, 7.69%
Neuropathy Peripheral (surface nerve damage): 1 person, 7.69%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 7.69%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Cogentin and have Diabetic nephropathy?

- Check whether Diabetic nephropathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cogentin:

Cogentin (7,692 reports)

Browse all side effects of Cogentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diabetic nephropathy:

Diabetic nephropathy (437 drugs)

Browse all the conditions that are associated with Diabetic nephropathy:

Diabetic nephropathy (603 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on benztropine mesylate (the active ingredients of Cogentin) and Cogentin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.