Cogentin and Inappropriate antidiuretic hormone secretion - a phase IV clinical study of FDA data

Summary:

Inappropriate antidiuretic hormone secretion is reported as a side effect among people who take Cogentin (benztropine mesylate), especially for people who are male, 40-49 old, also take Geodon, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Inappropriate antidiuretic hormone secretion when taking Cogentin. It is created by eHealthMe based on reports of 7,418 people who have side effects when taking Cogentin from the FDA, and is updated regularly.

What is Cogentin?

Cogentin has active ingredients of benztropine mesylate. It is often used in tardive dyskinesia. eHealthMe is studying from 7,692 Cogentin users. Check the latest studies of Cogentin.

What is Inappropriate antidiuretic hormone secretion?

Inappropriate antidiuretic hormone secretion is found to be associated with 669 drugs and 1,039 conditions by eHealthMe. Check the latest studies of Inappropriate antidiuretic hormone secretion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 19, 2026

7,418 people reported to have side effects when taking Cogentin.
Among them, 30 people (0.4%) have Inappropriate antidiuretic hormone secretion.

Could Cogentin cause Inappropriate antidiuretic hormone secretion?

Among these 30 people:

What is the gender of people who have Inappropriate antidiuretic hormone secretion when taking Cogentin? *

  • female: 6.9 %
  • male: 93.1 %

What is the age of people who have Inappropriate antidiuretic hormone secretion when taking Cogentin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 46.67 %
  • 50-59: 20.0 %
  • 60+: 33.33 %

What are other drugs people take besides Cogentin? *

  1. Geodon: 19 people, 63.33%
  2. Zyrtec: 18 people, 60.00%
  3. Nasonex: 18 people, 60.00%
  4. Lovenox: 18 people, 60.00%
  5. Lisinopril: 18 people, 60.00%
  6. Shark Cartilage: 18 people, 60.00%
  7. Sinemet: 18 people, 60.00%
  8. Klor-Con: 18 people, 60.00%
  9. Haldol: 18 people, 60.00%
  10. Flonase: 18 people, 60.00%

What are other side effects people have besides Inappropriate antidiuretic hormone secretion? *

  1. Drowsiness: 28 people, 93.33%
  2. Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 19 people, 63.33%
  3. Disturbance In Attention: 19 people, 63.33%
  4. Infection: 18 people, 60.00%
  5. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 18 people, 60.00%
  6. Hypoacusis (loss of hearing): 18 people, 60.00%
  7. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 18 people, 60.00%
  8. Wound Dehiscence (a surgical incision reopens either internally or externally): 18 people, 60.00%
  9. Headache (pain in head): 18 people, 60.00%
  10. Dizziness: 18 people, 60.00%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 14 people, 46.67%
  2. Depression: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Cogentin and have Inappropriate antidiuretic hormone secretion?

- Check whether Inappropriate antidiuretic hormone secretion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cogentin:

Inappropriate antidiuretic hormone secretion treatments and more:

How severe was Inappropriate antidiuretic hormone secretion and when was it recovered:

Expand to all the drugs that have ingredients of benztropine mesylate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cogentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Inappropriate antidiuretic hormone secretion:

Browse all the conditions that are associated with Inappropriate antidiuretic hormone secretion:


How the study uses the data?

The study uses data from the FDA. It is based on benztropine mesylate (the active ingredients of Cogentin) and Cogentin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: