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Colace and Hostility - a phase IV clinical study of FDA data

Summary:

Hostility is reported as a side effect among people who take Colace (docusate ), especially for people who are female, 60+ old, also take Neurontin, and have Mood swings.

The phase IV clinical study analyzes which people have Hostility when taking Colace. It is created by eHealthMe based on reports of 41,100 people who have side effects when taking Colace from the FDA, and is updated regularly.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,840 Colace users. Check the latest studies of Colace.

What is Hostility?

Hostility is found to be associated with 395 drugs and 423 conditions by eHealthMe. Check the latest studies of Hostility.

On Dec, 18, 2025

41,100 people reported to have side effects when taking Colace.
Among them, 11 people (0.03%) have Hostility.

Could Colace cause Hostility?

Among these 11 people:

What is the gender of people who have Hostility when taking Colace? *

  • female: 72.73 %
  • male: 27.27 %

What is the age of people who have Hostility when taking Colace? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 10 %
  • 30-39: 0.0 %
  • 40-49: 30 %
  • 50-59: 30 %
  • 60+: 30 %

What are other drugs people take besides Colace? *

  1. Neurontin: 5 people, 45.45%
  2. Zyprexa: 3 people, 27.27%
  3. Depakote: 3 people, 27.27%
  4. Ativan: 2 people, 18.18%
  5. Clozapine: 2 people, 18.18%
  6. Cogentin: 2 people, 18.18%
  7. Vitamin E: 2 people, 18.18%
  8. Sonata: 2 people, 18.18%
  9. Risperdal: 2 people, 18.18%
  10. Oxazepam: 2 people, 18.18%

What are other side effects people have besides Hostility? *

  1. Aggression: 8 people, 72.73%
  2. Agitation (state of anxiety or nervous excitement): 5 people, 45.45%
  3. Drug Ineffective: 3 people, 27.27%
  4. Gingivitis (inflammation of gums): 3 people, 27.27%
  5. Joint Swelling: 3 people, 27.27%
  6. Tooth Abscess (pus formation in tooth): 3 people, 27.27%
  7. Oedema Peripheral (superficial swelling): 3 people, 27.27%
  8. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 3 people, 27.27%
  9. Psychotic Disorder: 2 people, 18.18%
  10. White Blood Cell Count Increased: 2 people, 18.18%

What are the existing conditions these people have? *

  1. Mood Swings (an extreme or rapid change in mood): 3 people, 27.27%
  2. Psychotic Disorder: 2 people, 18.18%
  3. Stress And Anxiety: 1 person, 9.09%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 9.09%
  5. Depression: 1 person, 9.09%
  6. Asthma: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Colace and have Hostility?

- Check whether Hostility is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Colace:

Hostility treatments and more:

How severe was Hostility and when was it recovered:

Expand to all the drugs that have ingredients of docusate :

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Colace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hostility:

Browse all the conditions that are associated with Hostility:

How the study uses the data?

The study uses data from the FDA. It is based on docusate (the active ingredients of Colace) and Colace (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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