Colace and Pyogenic granuloma - a phase IV clinical study of FDA data

Summary:

Pyogenic granuloma is reported as a side effect among people who take Colace (docusate ), especially for people who are male, 60+ old, also take Prednisone, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Pyogenic granuloma when taking Colace. It is created by eHealthMe based on reports of 41,100 people who have side effects when taking Colace from the FDA, and is updated regularly.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

What is Pyogenic granuloma?

Pyogenic granuloma (small, raised, red bumps on the skin) is found to be associated with 89 drugs and 237 conditions by eHealthMe. Check the latest studies of Pyogenic granuloma.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

41,100 people reported to have side effects when taking Colace.
Among them, 12 people (0.03%) have Pyogenic granuloma.

Among these 12 people:

What is the gender of people who have Pyogenic granuloma when taking Colace? *

female: 50 %
male: 50 %

What is the age of people who have Pyogenic granuloma when taking Colace? *

What are other drugs people take besides Colace? *

What are other side effects people have besides Pyogenic granuloma? *

Osteomyelitis (infection of bone): 11 people, 91.67%
Stress And Anxiety: 11 people, 91.67%
Neuropathy Peripheral (surface nerve damage): 11 people, 91.67%
Osteonecrosis Of Jaw (death of bone of jaw): 11 people, 91.67%
Pain: 11 people, 91.67%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 11 people, 91.67%
Primary Sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone): 11 people, 91.67%
Injury: 11 people, 91.67%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 11 people, 91.67%
Anaemia (lack of blood): 11 people, 91.67%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 58.33%
Stress And Anxiety: 1 person, 8.33%
Postpartum Depression (depression suffered by a mother following childbirth): 1 person, 8.33%
Panic Disorder: 1 person, 8.33%
High Blood Pressure: 1 person, 8.33%
Depression: 1 person, 8.33%
Anaemia (lack of blood): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Colace and have Pyogenic granuloma?

- Check whether Pyogenic granuloma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Colace:

Colace (41,841 reports)

Browse all side effects of Colace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pyogenic granuloma:

Pyogenic granuloma (89 drugs)

Browse all the conditions that are associated with Pyogenic granuloma:

Pyogenic granuloma (237 conditions)

Related publications that referenced our studies

Ghalayani P, Hajisadeghi S, Babadi F, "Extragingival pyogenic granuloma associated with medication: Report of an unusual case", Dental research journal, 2014 Jan .
Yazdanian S, Parish LC, Lambert PC, Lambert WC, "Pyogenic granuloma: an enigma within a paradox or a solution in search of a problem", Skinmed, 2014 Jan .
Ghalayani P, Hajisadeghi S, Babadi F, "Extragingival pyogenic granuloma associated with medication: Report of an unusual case", Dental research journal, 2014 Jan .
Yazdanian S, Parish LC, Lambert PC, Lambert WC, "Pyogenic granuloma: an enigma within a paradox or a solution in search of a problem", Skinmed, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on docusate (the active ingredients of Colace) and Colace (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.