Colchicine and Gastrointestinal inflammation - a phase IV clinical study of FDA data

Summary:

Gastrointestinal inflammation is reported as a side effect among people who take Colchicine (colchicine), especially for people who are male, 40-49 old, have been taking the drug for 1 - 6 months also take Jakafi, and have Primary myelofibrosis.

The phase IV clinical study analyzes which people have Gastrointestinal inflammation when taking Colchicine. It is created by eHealthMe based on reports of 21,541 people who have side effects when taking Colchicine from the FDA, and is updated regularly.

What is Colchicine?

Colchicine has active ingredients of colchicine. It is often used in gout. eHealthMe is studying from 21,826 Colchicine users. Check the latest studies of Colchicine.

What is Gastrointestinal inflammation?

Gastrointestinal inflammation (inflammation of stomach and intestine) is found to be associated with 538 drugs and 548 conditions by eHealthMe. Check the latest studies of Gastrointestinal inflammation.

On Jul, 04, 2026

21,541 people reported to have side effects when taking Colchicine.
Among them, 12 people (0.06%) have Gastrointestinal inflammation.

Could Colchicine cause Gastrointestinal inflammation?

Among these 12 people:

How long have people been on Colchicine when they have Gastrointestinal inflammation? *

What is the gender of people who have Gastrointestinal inflammation when taking Colchicine? *

female: 50 %
male: 50 %

What is the age of people who have Gastrointestinal inflammation when taking Colchicine? *

What are other drugs people take besides Colchicine? *

What are other side effects people have besides Gastrointestinal inflammation? *

Pain: 6 people, 50.00%
Abdominal Distension: 6 people, 50.00%
Fatigue (feeling of tiredness): 6 people, 50.00%
Rashes (redness): 6 people, 50.00%
Paleness (unusual lightness of skin colour): 4 people, 33.33%
Thrombocytopenia (decrease of platelets in blood): 4 people, 33.33%
Abdominal Pain: 4 people, 33.33%
Haemoglobin Decreased: 4 people, 33.33%
Malaise (a feeling of general discomfort or uneasiness): 4 people, 33.33%
Dyspnea (difficult or laboured breathing): 4 people, 33.33%

What are the existing conditions these people have? *

Primary Myelofibrosis (primary disorder of the bone marrow): 5 people, 41.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 16.67%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 16.67%
Sleep Disorder: 1 person, 8.33%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 1 person, 8.33%
Ovarian Cancer (cancer of ovary): 1 person, 8.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 8.33%
Enteritis (inflammation of the small intestine): 1 person, 8.33%
Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 8.33%
Abdominal Pain: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Colchicine and have Gastrointestinal inflammation?

- Check whether Gastrointestinal inflammation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Colchicine:

Colchicine (21,826 reports)

Browse all side effects of Colchicine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gastrointestinal inflammation:

Gastrointestinal inflammation (538 drugs)

Browse all the conditions that are associated with Gastrointestinal inflammation:

Gastrointestinal inflammation (548 conditions)

Related publications that referenced our studies

Schwerd T, Pandey S, Yang HT, Bagola K, Jameson E, Jung J, Lachmann RH, Shah N, Patel SY, Booth C, Runz H, "Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann–Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn9s disease", Gut, 2016 Mar .
Schwerd T, Pandey S, Yang HT, Bagola K, Jameson E, Jung J, Lachmann RH, Shah N, Patel SY, Booth C, Runz H, "Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann–Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn9s disease", Gut, 2016 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on colchicine (the active ingredients of Colchicine) and Colchicine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.