Combivent and Hyperbilirubinaemia - a phase IV clinical study of FDA data

Summary:

Hyperbilirubinaemia is reported as a side effect among people who take Combivent (albuterol sulfate; ipratropium bromide), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Digoxin, and have Hypersensitivity.

The phase IV clinical study analyzes which people have Hyperbilirubinaemia when taking Combivent. It is created by eHealthMe based on reports of 35,104 people who have side effects when taking Combivent from the FDA, and is updated regularly.

What is Combivent?

Combivent has active ingredients of albuterol sulfate; ipratropium bromide. It is often used in asthma. eHealthMe is studying from 35,341 Combivent users. Check the latest studies of Combivent.

What is Hyperbilirubinaemia?

Hyperbilirubinaemia (excess of bilirubin in the blood) is found to be associated with 905 drugs and 1,074 conditions by eHealthMe. Check the latest studies of Hyperbilirubinaemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

35,104 people reported to have side effects when taking Combivent.
Among them, 14 people (0.04%) have Hyperbilirubinaemia.

Could Combivent cause Hyperbilirubinaemia?

Among these 14 people:

How long have people been on Combivent when they have Hyperbilirubinaemia? *

What is the gender of people who have Hyperbilirubinaemia when taking Combivent? *

female: 71.43 %
male: 28.57 %

What is the age of people who have Hyperbilirubinaemia when taking Combivent? *

What are other drugs people take besides Combivent? *

What are other side effects people have besides Hyperbilirubinaemia? *

High Blood Pressure: 5 people, 35.71%
Nausea (feeling of having an urge to vomit): 5 people, 35.71%
Abdominal Pain: 4 people, 28.57%
Acute Kidney Failure: 4 people, 28.57%
Pneumonia: 4 people, 28.57%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 28.57%
Gallstones (stone formation by bile component): 4 people, 28.57%
Fatigue (feeling of tiredness): 4 people, 28.57%
Septic Shock (shock due to blood infection): 4 people, 28.57%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 4 people, 28.57%

What are the existing conditions these people have? *

Cardiac Disorder: 3 people, 21.43%
Hypersensitivity: 3 people, 21.43%
Upper Respiratory Tract Infection: 2 people, 14.29%
Joint Pain: 2 people, 14.29%
Back Pain: 2 people, 14.29%
Drug Dependence: 2 people, 14.29%
Affective Disorder (mental disorder): 2 people, 14.29%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 14.29%
Spinal Pain (pain in spine): 2 people, 14.29%
Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Combivent and have Hyperbilirubinaemia?

- Check whether Hyperbilirubinaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Combivent:

Combivent (35,341 reports)

Hyperbilirubinaemia treatments and more:

Hyperbilirubinaemia (13,115 reports)

How severe was Hyperbilirubinaemia and when was it recovered:

Hyperbilirubinaemia in Combivent

Expand to all the drugs that have ingredients of albuterol sulfate; ipratropium bromide:

Hyperbilirubinaemia and drugs with ingredients of albuterol sulfate; ipratropium bromide

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Combivent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperbilirubinaemia:

Hyperbilirubinaemia (905 drugs)

Browse all the conditions that are associated with Hyperbilirubinaemia:

Hyperbilirubinaemia (1,074 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on albuterol sulfate; ipratropium bromide (the active ingredients of Combivent) and Combivent (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.