Combivent and Sudden cardiac death - a phase IV clinical study of FDA data

Summary:

Sudden cardiac death is reported as a side effect among people who take Combivent (albuterol sulfate; ipratropium bromide), especially for people who are male, 60+ old, also take Albuterol, and have Cardiac failure chronic.

The study is created by eHealthMe based on reports of 35,104 people who have side effects when taking Combivent from the FDA, and is updated regularly.

What is Combivent?

Combivent has active ingredients of albuterol sulfate; ipratropium bromide. It is often used in asthma. eHealthMe is studying from 35,341 Combivent users. Check the latest studies of Combivent.

On Jul, 10, 2026

35,104 people reported to have side effects when taking Combivent.
Among them, 13 people (0.04%) died.

Could Combivent cause Sudden cardiac death?

Among these 13 people:

What is the gender of people who died when taking Combivent? *

female: 38.46 %
male: 61.54 %

What is the age of people who died when taking Combivent? *

What are other drugs people take besides Combivent? *

What are other side effects people have before they died? *

Heart Attack: 5 people, 38.46%
Cardiac Failure Congestive: 5 people, 38.46%
Multiple Injuries: 4 people, 30.77%
Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 3 people, 23.08%
Pneumonia: 3 people, 23.08%
Diabetes: 3 people, 23.08%
Cardiac Fibrillation (uncontrolled muscle contraction of heart): 2 people, 15.38%
Metastases To Lymph Nodes (cancer spreads to lymph node): 2 people, 15.38%
Cardiac Arrest: 2 people, 15.38%
Leukocytosis (increased white blood cells): 2 people, 15.38%

What are the existing conditions these people have? *

Erection Problems: 2 people, 15.38%
Cardiac Failure Chronic: 2 people, 15.38%
Type 2 Diabetes: 1 person, 7.69%
Osteoporosis (bones weak and more likely to break): 1 person, 7.69%
Multiple Myeloma (cancer of the plasma cells): 1 person, 7.69%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Combivent:

Combivent (35,341 reports)

Expand to all the drugs that have ingredients of albuterol sulfate; ipratropium bromide:

Sudden cardiac death and drugs with ingredients of albuterol sulfate; ipratropium bromide

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Combivent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sudden cardiac death:

Sudden cardiac death (350 drugs)

Browse all the conditions that are associated with Sudden cardiac death:

Sudden cardiac death (417 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on albuterol sulfate; ipratropium bromide (the active ingredients of Combivent) and Combivent (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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