Combivir and Foot deformity - a phase IV clinical study of FDA data

Summary:

Foot deformity is reported as a side effect among people who take Combivir (lamivudine; zidovudine), especially for people who are male, 0-1 old, have been taking the drug for 6 - 12 months also take Norvir, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Foot deformity when taking Combivir. It is created by eHealthMe based on reports of 15,371 people who have side effects when taking Combivir from the FDA, and is updated regularly.

What is Combivir?

Combivir has active ingredients of lamivudine; zidovudine. It is often used in hiv infection. eHealthMe is studying from 15,450 Combivir users. Check the latest studies of Combivir.

What is Foot deformity?

Foot deformity (functional disability of foot) is found to be associated with 909 drugs and 707 conditions by eHealthMe. Check the latest studies of Foot deformity.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 31, 2026

15,371 people reported to have side effects when taking Combivir.
Among them, 21 people (0.14%) have Foot deformity.

Could Combivir cause Foot deformity?

Among these 21 people:

How long have people been on Combivir when they have Foot deformity? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 50 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Foot deformity when taking Combivir? *

  • female: 50 %
  • male: 50 %

What is the age of people who have Foot deformity when taking Combivir? *

  • 0-1: 100 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Combivir? *

  1. Norvir: 14 people, 66.67%
  2. Sustiva: 10 people, 47.62%
  3. Fortovase: 6 people, 28.57%
  4. Zometa: 4 people, 19.05%
  5. Reyataz: 4 people, 19.05%
  6. Ms Contin: 4 people, 19.05%
  7. Neurontin: 4 people, 19.05%
  8. Percocet: 3 people, 14.29%
  9. Kaletra: 3 people, 14.29%
  10. Keflex: 3 people, 14.29%

What are other side effects people have besides Foot deformity? *

  1. Deformity (disfigurement): 12 people, 57.14%
  2. Neural Tube Defect (birth defects of the brain, spine, or spinal cord): 10 people, 47.62%
  3. Urogenital Disorder: 9 people, 42.86%
  4. Dysmorphism (difference of body structure that is suggestive of a congenital disorder): 6 people, 28.57%
  5. Imperforate Anus (congenital defect of the anus; there is partial or complete obstruction of the anal opening): 5 people, 23.81%
  6. Abdominal Pain: 4 people, 19.05%
  7. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 4 people, 19.05%
  8. Intervertebral Disc Degeneration (spinal disc degeneration): 4 people, 19.05%
  9. Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 4 people, 19.05%
  10. Osteonecrosis Of Jaw (death of bone of jaw): 4 people, 19.05%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 3 people, 14.29%
  2. Metastases To Bone (cancer spreads to bone): 1 person, 4.76%
  3. Drug Exposure During Pregnancy: 1 person, 4.76%
  4. Breast Cancer: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Combivir and have Foot deformity?

- Check whether Foot deformity is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Combivir:

Foot deformity treatments and more:

How severe was Foot deformity and when was it recovered:

Expand to all the drugs that have ingredients of lamivudine; zidovudine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Combivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Foot deformity:

Browse all the conditions that are associated with Foot deformity:


How the study uses the data?

The study uses data from the FDA. It is based on lamivudine; zidovudine (the active ingredients of Combivir) and Combivir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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