Combivir and Umbilical hernia - a phase IV clinical study of FDA data

Summary:

Umbilical hernia is reported as a side effect among people who take Combivir (lamivudine; zidovudine), especially for people who are female, 0-1 old, have been taking the drug for 1 - 6 months also take Viramune, and have Drug exposure during pregnancy.

The phase IV clinical study analyzes which people have Umbilical hernia when taking Combivir. It is created by eHealthMe based on reports of 15,371 people who have side effects when taking Combivir from the FDA, and is updated regularly.

What is Combivir?

Combivir has active ingredients of lamivudine; zidovudine. It is often used in hiv infection. eHealthMe is studying from 15,450 Combivir users. Check the latest studies of Combivir.

What is Umbilical hernia?

Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button) is found to be associated with 643 drugs and 676 conditions by eHealthMe. Check the latest studies of Umbilical hernia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

15,371 people reported to have side effects when taking Combivir.
Among them, 40 people (0.26%) have Umbilical hernia.

Among these 40 people:

How long have people been on Combivir when they have Umbilical hernia? *

What is the gender of people who have Umbilical hernia when taking Combivir? *

female: 52.63 %
male: 47.37 %

What is the age of people who have Umbilical hernia when taking Combivir? *

What are other drugs people take besides Combivir? *

What are other side effects people have besides Umbilical hernia? *

Abdominal Distension: 19 people, 47.50%
Blood Creatine Phosphokinase Increased: 11 people, 27.50%
Neutropenia Neonatal (an abnormally low number of neutrophils in below a month baby): 11 people, 27.50%
Thrombocythaemia (an increased number of platelets in the circulating blood): 9 people, 22.50%
Hepatomegaly (abnormal enlargement of the liver): 8 people, 20.00%
Blood Lactic Acid Increased: 6 people, 15.00%
Strabismus (a disorder in which the two eyes do not line up in the same direction): 6 people, 15.00%
Anaemia Macrocytic (a macrocytic class of anaemia): 5 people, 12.50%
Diarrhea: 5 people, 12.50%
Premature Baby: 5 people, 12.50%

What are the existing conditions these people have? *

Drug Exposure During Pregnancy: 7 people, 17.50%
Maternal Exposure During Pregnancy (use of substance during pregnancy): 4 people, 10.00%
Vertical Infection Transmission: 1 person, 2.50%
Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 1 person, 2.50%
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 1 person, 2.50%
Ill-Defined Disorder: 1 person, 2.50%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 1 person, 2.50%
Diarrhea: 1 person, 2.50%
Cardiac Disorder: 1 person, 2.50%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 2.50%

* Approximation only. Some reports may have incomplete information.

Do you take Combivir and have Umbilical hernia?

- Check whether Umbilical hernia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Combivir:

Combivir (15,450 reports)

Browse all side effects of Combivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Umbilical hernia:

Umbilical hernia (643 drugs)

Browse all the conditions that are associated with Umbilical hernia:

Umbilical hernia (676 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lamivudine; zidovudine (the active ingredients of Combivir) and Combivir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.