Combivir and Ventricular dysfunction - a phase IV clinical study of FDA data

Summary:

Ventricular dysfunction is reported as a side effect among people who take Combivir (lamivudine; zidovudine), especially for people who are male, 30-39 old, have been taking the drug for < 1 month also take Retrovir, and have Depression.

The phase IV clinical study analyzes which people have Ventricular dysfunction when taking Combivir. It is created by eHealthMe based on reports of 15,371 people who have side effects when taking Combivir from the FDA, and is updated regularly.

What is Combivir?

Combivir has active ingredients of lamivudine; zidovudine. It is often used in hiv infection. eHealthMe is studying from 15,450 Combivir users. Check the latest studies of Combivir.

What is Ventricular dysfunction?

Ventricular dysfunction (heart dysfunction) is found to be associated with 456 drugs and 551 conditions by eHealthMe. Check the latest studies of Ventricular dysfunction.

On Jul, 15, 2026

15,371 people reported to have side effects when taking Combivir.
Among them, 11 people (0.07%) have Ventricular dysfunction.

Could Combivir cause Ventricular dysfunction?

Among these 11 people:

How long have people been on Combivir when they have Ventricular dysfunction? *

What is the gender of people who have Ventricular dysfunction when taking Combivir? *

female: 9.09 %
male: 90.91 %

What is the age of people who have Ventricular dysfunction when taking Combivir? *

What are other drugs people take besides Combivir? *

What are other side effects people have besides Ventricular dysfunction? *

Dyspnea (difficult or laboured breathing): 8 people, 72.73%
Cardiac Failure: 6 people, 54.55%
Congestive Cardiomyopathy (weakening of heart muscle): 6 people, 54.55%
Fatigue (feeling of tiredness): 4 people, 36.36%
Dyspnea Exertional: 3 people, 27.27%
Lung Disorder (lung disease): 3 people, 27.27%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 3 people, 27.27%
Hypokalemia (low potassium): 3 people, 27.27%
Histiocytosis Haematophagic: 3 people, 27.27%
Hepatomegaly (abnormal enlargement of the liver): 3 people, 27.27%

What are the existing conditions these people have? *

Depression: 3 people, 27.27%
Viral Infection: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Combivir and have Ventricular dysfunction?

- Check whether Ventricular dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Combivir:

Combivir (15,450 reports)

Browse all side effects of Combivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ventricular dysfunction:

Ventricular dysfunction (456 drugs)

Browse all the conditions that are associated with Ventricular dysfunction:

Ventricular dysfunction (551 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lamivudine; zidovudine (the active ingredients of Combivir) and Combivir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.