Commit and Pruritus - a phase IV clinical study of FDA data

Summary:

Pruritus is reported as a side effect among people who take Commit (nicotine polacrilex), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Nicoderm Cq, and have Bipolar disorder.

The phase IV clinical study analyzes which people have Pruritus when taking Commit. It is created by eHealthMe based on reports of 4,836 people who have side effects when taking Commit from the FDA, and is updated regularly.

What is Commit?

Commit has active ingredients of nicotine polacrilex. eHealthMe is studying from 4,842 Commit users. Check the latest studies of Commit.

What is Pruritus?

Pruritus (severe itching of the skin) is found to be associated with 3,390 drugs and 4,545 conditions by eHealthMe. Check the latest studies of Pruritus.

On Jun, 20, 2026

4,836 people reported to have side effects when taking Commit.
Among them, 23 people (0.48%) have Pruritus.

Among these 23 people:

How long have people been on Commit when they have Pruritus? *

What is the gender of people who have Pruritus when taking Commit? *

female: 77.27 %
male: 22.73 %

What is the age of people who have Pruritus when taking Commit? *

What are other drugs people take besides Commit? *

What are other side effects people have besides Pruritus? *

Rashes (redness): 10 people, 43.48%
Urticaria (rash of round, red welts on the skin that itch intensely): 5 people, 21.74%
Hypersensitivity: 4 people, 17.39%
Nausea (feeling of having an urge to vomit): 3 people, 13.04%
Oral Discomfort (pain or irritation in mouth): 2 people, 8.70%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 2 people, 8.70%
Haemorrhage (bleeding): 2 people, 8.70%
Hypoaesthesia (reduced sense of touch or sensation): 2 people, 8.70%
Weakness: 2 people, 8.70%
Memory Loss: 2 people, 8.70%

What are the existing conditions these people have? *

Bipolar Disorder (mood disorder): 2 people, 8.70%
Quit Smoking: 1 person, 4.35%
Ill-Defined Disorder: 1 person, 4.35%
High Blood Pressure: 1 person, 4.35%
Diabetes: 1 person, 4.35%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Commit and have Pruritus?

- Check whether Pruritus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Commit:

Commit (4,842 reports)

Pruritus treatments and more:

Pruritus (398,819 reports)

Browse all side effects of Commit:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pruritus:

Pruritus (3,390 drugs)

Browse all the conditions that are associated with Pruritus:

Pruritus (4,545 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nicotine polacrilex (the active ingredients of Commit) and Commit (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.