Commit and Retching - a phase IV clinical study of FDA data

Summary:

Retching is reported as a side effect among people who take Commit (nicotine polacrilex), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Nicoderm Cq, and have Quit smoking.

The phase IV clinical study analyzes which people have Retching when taking Commit. It is created by eHealthMe based on reports of 4,836 people who have side effects when taking Commit from the FDA, and is updated regularly.

What is Commit?

Commit has active ingredients of nicotine polacrilex. eHealthMe is studying from 4,842 Commit users. Check the latest studies of Commit.

What is Retching?

Retching (strong involuntary effort to vomit) is found to be associated with 1,276 drugs and 1,244 conditions by eHealthMe. Check the latest studies of Retching.

On Jan, 30, 2026

4,836 people reported to have side effects when taking Commit.
Among them, 93 people (1.92%) have Retching.

Among these 93 people:

* Approximation only. Some reports may have incomplete information.

Do you take Commit and have Retching?

- Check whether Retching is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Commit:

Commit (4,842 reports)

Retching treatments and more:

Retching (23,331 reports)

How severe was Retching and when was it recovered:

Retching in Commit

Expand to all the drugs that have ingredients of nicotine polacrilex:

Retching and drugs with ingredients of nicotine polacrilex

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Commit side effects:

Browse all side effects of Commit:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Retching:

Browse all the drugs that are associated with Retching:

Retching (1,276 drugs)

Common conditions associated with Retching:

Hypertension aggravated: 975 reports
High blood pressure: 968 reports
Pain: 782 reports
Alternative medicine - pain relief: 776 reports
Pulmonary arterial hypertension: 744 reports
Ms: 710 reports
Depression: 674 reports
Antidepressant therapy: 673 reports
Type 2 diabetes: 610 reports
Ra: 589 reports
Blood triglycerides abnormal: 580 reports
Rheumatoid arthritis: 558 reports
Hypercholesterolaemia: 541 reports
Stress: 486 reports
Asthma: 466 reports
Exercise-induced asthma: 464 reports
Gastrooesophageal reflux disease: 443 reports
Anxiety: 441 reports
Osteoporosis: 425 reports
Diabetes: 424 reports
Ovarian cancer: 413 reports
Dm: 407 reports
Crohn's disease: 405 reports
Chronic obstructive pulmonary disease: 353 reports
Add: 328 reports
Diabetes mellitus non-insulin-dependent: 324 reports
Smoking and smokeless tobacco: 317 reports
Cessation of smoking: 313 reports
Cataplexy: 301 reports
Attention deficit/hyperactivity disorder: 267 reports
Parkinson's disease: 252 reports
Hepatitis c: 248 reports
Idiopathic pulmonary fibrosis: 237 reports
Low thyroid: 230 reports
Migraine: 223 reports
Insomnia: 213 reports
Hypersensitivity: 208 reports
Diarrhoea: 205 reports
Breast cancer: 201 reports
Sleep disorder: 187 reports
Constipation: 181 reports
Blood pressure abnormal: 180 reports
Multiple myeloma: 176 reports
Stool softener: 175 reports
Back pain: 171 reports
Psoriatic arthropathy aggravated: 170 reports
Cardiac disorder: 160 reports
Cancer - kidney: 159 reports
Pulmonary hypertension: 154 reports
Headache: 148 reports
Prostate cancer: 146 reports
Cancer - prostate: 145 reports
Breast cancer metastatic: 144 reports
Atrial flutter: 140 reports
Thyroid function test abnormal: 139 reports
Bipolar disorder: 136 reports
Fibromyalgia: 133 reports
Ulcerative colitis: 132 reports
Drowsiness: 126 reports
Arthritis: 124 reports
Preventive health care: 116 reports
Indigestion: 115 reports
Seizure disorder: 105 reports
Birth control and family planning: 104 reports
Joint pain: 103 reports

Browse all the conditions that are associated with Retching:

Retching (1,244 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nicotine polacrilex (the active ingredients of Commit) and Commit (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.