Commit and Sleeping difficulty - a phase IV clinical study of FDA data

Summary:

Sleeping difficulty is reported as a side effect among people who take Commit (nicotine polacrilex), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Nicoderm Cq, and have Quit smoking.

The phase IV clinical study analyzes which people have Sleeping difficulty when taking Commit. It is created by eHealthMe based on reports of 4,836 people who have side effects when taking Commit from the FDA, and is updated regularly.

What is Commit?

Commit has active ingredients of nicotine polacrilex. eHealthMe is studying from 4,842 Commit users. Check the latest studies of Commit.

What is Sleeping difficulty?

Sleeping difficulty (difficult sleeping) is found to be associated with 4,140 drugs and 5,376 conditions by eHealthMe. Check the latest studies of Sleeping difficulty.

On May, 02, 2026

4,836 people reported to have side effects when taking Commit.
Among them, 46 people (0.95%) have Sleeping difficulty.

Among these 46 people:

How long have people been on Commit when they have Sleeping difficulty? *

What is the gender of people who have Sleeping difficulty when taking Commit? *

female: 70.45 %
male: 29.55 %

What is the age of people who have Sleeping difficulty when taking Commit? *

What are other drugs people take besides Commit? *

What are other side effects people have besides Sleeping difficulty? *

Nausea (feeling of having an urge to vomit): 8 people, 17.39%
Nicotine Dependence: 6 people, 13.04%
Feeling Abnormal: 5 people, 10.87%
Malaise (a feeling of general discomfort or uneasiness): 5 people, 10.87%
Headache (pain in head): 5 people, 10.87%
Stress And Anxiety: 5 people, 10.87%
Nervousness: 4 people, 8.70%
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough): 4 people, 8.70%
Stomatitis (inflammation of mucous membrane of mouth): 4 people, 8.70%
Fatigue (feeling of tiredness): 3 people, 6.52%

What are the existing conditions these people have? *

Quit Smoking: 6 people, 13.04%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 2.17%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 2.17%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 2.17%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 2.17%

* Approximation only. Some reports may have incomplete information.

Do you take Commit and have Sleeping difficulty?

- Check whether Sleeping difficulty is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Commit:

Commit (4,842 reports)

Browse all side effects of Commit:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sleeping difficulty:

Sleeping difficulty (4,140 drugs)

Browse all the conditions that are associated with Sleeping difficulty:

Sleeping difficulty (5,376 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nicotine polacrilex (the active ingredients of Commit) and Commit (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.