Commit and Tooth disorder - a phase IV clinical study of FDA data

Summary:

Tooth disorder is reported as a side effect among people who take Commit (nicotine polacrilex), especially for people who are female, 60+ old, also take Nicorette, and have Depression.

The phase IV clinical study analyzes which people have Tooth disorder when taking Commit. It is created by eHealthMe based on reports of 4,836 people who have side effects when taking Commit from the FDA, and is updated regularly.

What is Commit?

Commit has active ingredients of nicotine polacrilex. eHealthMe is studying from 4,842 Commit users. Check the latest studies of Commit.

What is Tooth disorder?

Tooth disorder (tooth disease) is found to be associated with 1,290 drugs and 1,176 conditions by eHealthMe. Check the latest studies of Tooth disorder.



On Nov, 30, 2025

4,836 people reported to have side effects when taking Commit.
Among them, 18 people (0.37%) have Tooth disorder.

Could Commit cause Tooth disorder?

Among these 18 people:

What is the gender of people who have Tooth disorder when taking Commit? *

  • female: 83.33 %
  • male: 16.67 %

What is the age of people who have Tooth disorder when taking Commit? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 23.08 %
  • 50-59: 30.77 %
  • 60+: 46.15 %

What are other drugs people take besides Commit? *

  1. Nicorette: 10 people, 55.56%
  2. Nicoderm Cq: 2 people, 11.11%
  3. Lorazepam: 1 person, 5.56%

What are other side effects people have besides Tooth disorder? *

  1. Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough): 4 people, 22.22%
  2. Dental Caries: 3 people, 16.67%
  3. Abdominal Pain Upper: 3 people, 16.67%
  4. Nicotine Dependence: 2 people, 11.11%
  5. Oral Pain: 1 person, 5.56%
  6. Nausea (feeling of having an urge to vomit): 1 person, 5.56%
  7. Mouth Ulcers: 1 person, 5.56%
  8. Mineral Deficiency (lack of mineral): 1 person, 5.56%
  9. Initial Insomnia (feeling of inadequate or poor-quality sleep): 1 person, 5.56%
  10. Tooth Injury: 1 person, 5.56%

What are the existing conditions these people have? *

  1. Quit Smoking: 1 person, 5.56%
  2. Depression: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Commit and have Tooth disorder?

- Check whether Tooth disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Commit:

Tooth disorder treatments and more:

How severe was Tooth disorder and when was it recovered:

Expand to all the drugs that have ingredients of nicotine polacrilex:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Commit:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tooth disorder:

Browse all the conditions that are associated with Tooth disorder:


How the study uses the data?

The study uses data from the FDA. It is based on nicotine polacrilex (the active ingredients of Commit) and Commit (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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