Compazine and Autoimmune disorder - a phase IV clinical study of FDA data

Summary:

Autoimmune disorder is reported as a side effect among people who take Compazine (prochlorperazine maleate), especially for people who are female, 60+ old, also take Tylenol, and have Ovarian cancer.

The phase IV clinical study analyzes which people have Autoimmune disorder when taking Compazine. It is created by eHealthMe based on reports of 13,599 people who have side effects when taking Compazine from the FDA, and is updated regularly.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in nausea and vomiting. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.

What is Autoimmune disorder?

Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue) is found to be associated with 716 drugs and 825 conditions by eHealthMe. Check the latest studies of Autoimmune disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

13,599 people reported to have side effects when taking Compazine.
Among them, 19 people (0.14%) have Autoimmune disorder.

Could Compazine cause Autoimmune disorder?

Among these 19 people:

What is the gender of people who have Autoimmune disorder when taking Compazine? *

female: 87.5 %
male: 12.5 %

What is the age of people who have Autoimmune disorder when taking Compazine? *

What are other drugs people take besides Compazine? *

What are other side effects people have besides Autoimmune disorder? *

Insomnia (sleeplessness): 15 people, 78.95%
Malaise (a feeling of general discomfort or uneasiness): 15 people, 78.95%
Abdominal Discomfort: 14 people, 73.68%
Dyspnea (difficult or laboured breathing): 13 people, 68.42%
Urinary Tract Infection: 13 people, 68.42%
Cough: 13 people, 68.42%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 11 people, 57.89%
Pain: 11 people, 57.89%
High Blood Pressure: 11 people, 57.89%
Fatigue (feeling of tiredness): 10 people, 52.63%

What are the existing conditions these people have? *

Ovarian Cancer (cancer of ovary): 10 people, 52.63%
Urinary Tract Infection: 9 people, 47.37%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 5 people, 26.32%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 4 people, 21.05%
Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 4 people, 21.05%
Muscle Disorder (muscle disease): 4 people, 21.05%
Metastases To Bone (cancer spreads to bone): 1 person, 5.26%
Insomnia (sleeplessness): 1 person, 5.26%
Chemical Eye Injury: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Compazine and have Autoimmune disorder?

- Check whether Autoimmune disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Compazine:

Compazine (13,646 reports)

Browse all side effects of Compazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Autoimmune disorder:

Autoimmune disorder (716 drugs)

Browse all the conditions that are associated with Autoimmune disorder:

Autoimmune disorder (825 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on prochlorperazine maleate (the active ingredients of Compazine) and Compazine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.