Compazine and Bone marrow failure - a phase IV clinical study of FDA data

Summary:

Bone marrow failure is reported as a side effect among people who take Compazine (prochlorperazine maleate), especially for people who are female, 60+ old, also take Zofran, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Bone marrow failure when taking Compazine. It is created by eHealthMe based on reports of 13,599 people who have side effects when taking Compazine from the FDA, and is updated regularly.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in indigestion. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.

What is Bone marrow failure?

Bone marrow failure is found to be associated with 1,015 drugs and 1,438 conditions by eHealthMe. Check the latest studies of Bone marrow failure.

On Jul, 13, 2026

13,599 people reported to have side effects when taking Compazine.
Among them, 35 people (0.26%) have Bone marrow failure.

Could Compazine cause Bone marrow failure?

Among these 35 people:

What is the gender of people who have Bone marrow failure when taking Compazine? *

female: 62.5 %
male: 37.5 %

What is the age of people who have Bone marrow failure when taking Compazine? *

What are other drugs people take besides Compazine? *

What are other side effects people have besides Bone marrow failure? *

Thrombocytopenia (decrease of platelets in blood): 16 people, 45.71%
Anaemia (lack of blood): 13 people, 37.14%
Diarrhea: 13 people, 37.14%
Dyspnea (difficult or laboured breathing): 11 people, 31.43%
Fatigue (feeling of tiredness): 11 people, 31.43%
High Blood Pressure: 11 people, 31.43%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 11 people, 31.43%
Back Pain: 10 people, 28.57%
Oedema Peripheral (superficial swelling): 9 people, 25.71%
Weakness: 9 people, 25.71%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 10 people, 28.57%
Pain: 6 people, 17.14%
Ovarian Cancer (cancer of ovary): 6 people, 17.14%
Breast Cancer Metastatic: 3 people, 8.57%
Breast Cancer: 3 people, 8.57%
Constipation: 2 people, 5.71%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 5.71%
High Blood Pressure: 2 people, 5.71%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 5.71%
Back Pain: 1 person, 2.86%

* Approximation only. Some reports may have incomplete information.

Do you take Compazine and have Bone marrow failure?

- Check whether Bone marrow failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Compazine:

Compazine (13,646 reports)

Browse all side effects of Compazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone marrow failure:

Bone marrow failure (1,015 drugs)

Browse all the conditions that are associated with Bone marrow failure:

Bone marrow failure (1,438 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on prochlorperazine maleate (the active ingredients of Compazine) and Compazine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.