Compazine and Hyperthyroidism - a phase IV clinical study of FDA data

Summary:

Hyperthyroidism is reported as a side effect among people who take Compazine (prochlorperazine maleate), especially for people who are female, 60+ old, also take Aredia, and have Hypothyroidism.

The phase IV clinical study analyzes which people have Hyperthyroidism when taking Compazine. It is created by eHealthMe based on reports of 13,599 people who have side effects when taking Compazine from the FDA, and is updated regularly.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in nausea and vomiting. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.

What is Hyperthyroidism?

Hyperthyroidism (over activity of the thyroid gland) is found to be associated with 1,026 drugs and 1,428 conditions by eHealthMe. Check the latest studies of Hyperthyroidism.

On Feb, 23, 2026

13,599 people reported to have side effects when taking Compazine.
Among them, 11 people (0.08%) have Hyperthyroidism.

Among these 11 people:

What is the gender of people who have Hyperthyroidism when taking Compazine? *

female: 81.82 %
male: 18.18 %

What is the age of people who have Hyperthyroidism when taking Compazine? *

What are other drugs people take besides Compazine? *

What are other side effects people have besides Hyperthyroidism? *

Rashes (redness): 8 people, 72.73%
High Blood Pressure: 7 people, 63.64%
Neuropathy Peripheral (surface nerve damage): 7 people, 63.64%
Stress And Anxiety: 7 people, 63.64%
Anaemia (lack of blood): 6 people, 54.55%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 54.55%
Dyspnea (difficult or laboured breathing): 6 people, 54.55%
Osteonecrosis Of Jaw (death of bone of jaw): 6 people, 54.55%
Abdominal Pain: 5 people, 45.45%
Bone Lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 5 people, 45.45%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 3 people, 27.27%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 27.27%
Anaemia (lack of blood): 2 people, 18.18%
Pain: 2 people, 18.18%
Breast Cancer: 2 people, 18.18%
Stress And Anxiety: 1 person, 9.09%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 9.09%
Blood Pressure Abnormal: 1 person, 9.09%
Breast Cancer Metastatic: 1 person, 9.09%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Compazine and have Hyperthyroidism?

- Check whether Hyperthyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Compazine:

Compazine (13,646 reports)

Hyperthyroidism treatments and more:

Hyperthyroidism (26,831 reports)

Browse all side effects of Compazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperthyroidism:

Hyperthyroidism (1,026 drugs)

Browse all the conditions that are associated with Hyperthyroidism:

Hyperthyroidism (1,428 conditions)

Related publications that referenced our studies

Dulani S, Dulani R, Lele S, Diagavane S, Anjankar S, Jaiswal N, Subramaniam PS, Juneja R, "Chronic Subdural Haematoma in a Case of Hyperthyroidism Presenting with Papilledema", Chinese Medicine, 2012 Dec .
Dulani S, Dulani R, Lele S, Diagavane S, Anjankar S, Jaiswal N, Subramaniam PS, Juneja R, "Chronic Subdural Haematoma in a Case of Hyperthyroidism Presenting with Papilledema", Chinese Medicine, 2012 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on prochlorperazine maleate (the active ingredients of Compazine) and Compazine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.