Complera and Depression - a phase IV clinical study of FDA data

Summary:

Depression is reported as a side effect among people who take Complera (emtricitabine; rilpivirine; tenofovir disoproxil fumarate), especially for people who are male, 40-49 old, have been taking the drug for 1 - 6 months also take Truvada, and have Cataplexy.

The phase IV clinical study analyzes which people have Depression when taking Complera. It is created by eHealthMe based on reports of 437 people who have side effects when taking Complera from the FDA, and is updated regularly.

What is Complera?

Complera has active ingredients of emtricitabine; rilpivirine; tenofovir disoproxil fumarate. It is often used in hiv infection. eHealthMe is studying from 474 Complera users. Check the latest studies of Complera.

What is Depression?

Depression is found to be associated with 3,167 drugs and 4,125 conditions by eHealthMe. Check the latest studies of Depression.

On Jul, 09, 2026

437 people reported to have side effects when taking Complera.
Among them, 14 people (3.2%) have Depression.

Among these 14 people:

How long have people been on Complera when they have Depression? *

What is the gender of people who have Depression when taking Complera? *

female: 42.86 %
male: 57.14 %

What is the age of people who have Depression when taking Complera? *

What are other drugs people take besides Complera? *

What are other side effects people have besides Depression? *

Suicidal Ideation: 2 people, 14.29%
Mood Swings (an extreme or rapid change in mood): 2 people, 14.29%
Weight Increased: 1 person, 7.14%
Headache (pain in head): 1 person, 7.14%
Cardiac Failure Congestive: 1 person, 7.14%
Chest Pain: 1 person, 7.14%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.14%
Diarrhea: 1 person, 7.14%
Dyspnea (difficult or laboured breathing): 1 person, 7.14%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 7.14%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 7.14%
Immune System Disorder: 1 person, 7.14%
High Blood Pressure: 1 person, 7.14%
Diabetes: 1 person, 7.14%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Complera and have Depression?

- Check whether Depression is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Complera:

Complera (474 reports)

Depression treatments and more:

Depression (652,144 reports)

How severe was Depression and when was it recovered:

Depression in Complera

Expand to all the drugs that have ingredients of emtricitabine; rilpivirine; tenofovir disoproxil fumarate:

Depression and drugs with ingredients of emtricitabine; rilpivirine; tenofovir disoproxil fumarate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Complera:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Depression:

Depression (3,167 drugs)

Browse all the conditions that are associated with Depression:

Depression (4,125 conditions)

Related publications that referenced our studies

Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .
Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on emtricitabine; rilpivirine; tenofovir disoproxil fumarate (the active ingredients of Complera) and Complera (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.