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Compro and Closed angle glaucoma - a phase IV clinical study of FDA data

Summary:

Closed angle glaucoma is reported as a side effect among people who take Compro (prochlorperazine), especially for people who are male, 60+ old, also take Vicodin, and have Agitation.

The phase IV clinical study analyzes which people have Closed angle glaucoma when taking Compro. It is created by eHealthMe based on reports of 191 people who have side effects when taking Compro from the FDA, and is updated regularly.

What is Compro?

Compro has active ingredients of prochlorperazine. eHealthMe is studying from 197 Compro users. Check the latest studies of Compro.

What is Closed angle glaucoma?

Closed angle glaucoma (pressure inside your eye rises quickly) is found to be associated with 1,913 drugs and 1,683 conditions by eHealthMe. Check the latest studies of Closed angle glaucoma.

On Jun, 22, 2026

191 people reported to have side effects when taking Compro.
Among them, 12 people (6.28%) have Closed angle glaucoma.

Could Compro cause Closed angle glaucoma?

Among these 12 people:

What is the gender of people who have Closed angle glaucoma when taking Compro? *

  • female: 0.0 %
  • male: 100 %

What is the age of people who have Closed angle glaucoma when taking Compro? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 33.33 %
  • 60+: 66.67 %

What are other drugs people take besides Compro? *

  1. Vicodin: 12 people, 100.00%
  2. Hydrocodone Bitartrate And Acetaminophen: 11 people, 91.67%
  3. Lexapro: 11 people, 91.67%
  4. Dexamethasone: 10 people, 83.33%
  5. Morphine Sulfate: 10 people, 83.33%
  6. Avelox: 10 people, 83.33%
  7. Biaxin: 10 people, 83.33%
  8. Flovent: 10 people, 83.33%
  9. Paxil: 10 people, 83.33%
  10. Nystatin: 10 people, 83.33%

What are other side effects people have besides Closed angle glaucoma? *

  1. Drug Dependence: 12 people, 100.00%
  2. Affective Disorder (mental disorder): 10 people, 83.33%
  3. Pain In Jaw: 10 people, 83.33%
  4. Osteonecrosis Of Jaw (death of bone of jaw): 10 people, 83.33%
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 10 people, 83.33%
  6. Neck Pain: 10 people, 83.33%
  7. Neck Mass (mass in neck): 10 people, 83.33%
  8. Nausea And Vomiting: 10 people, 83.33%
  9. Nausea (feeling of having an urge to vomit): 10 people, 83.33%
  10. Multiple Myeloma (cancer of the plasma cells): 10 people, 83.33%

What are the existing conditions these people have? *

  1. Headache (pain in head): 2 people, 16.67%
  2. Fever: 2 people, 16.67%
  3. Agitation (state of anxiety or nervous excitement): 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Compro and have Closed angle glaucoma?

- Check whether Closed angle glaucoma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Compro:

Closed angle glaucoma treatments and more:

How severe was Closed angle glaucoma and when was it recovered:

Expand to all the drugs that have ingredients of prochlorperazine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Compro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Closed angle glaucoma:

Browse all the conditions that are associated with Closed angle glaucoma:

How the study uses the data?

The study uses data from the FDA. It is based on prochlorperazine (the active ingredients of Compro) and Compro (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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