Concerta and Aortic valve incompetence - a phase IV clinical study of FDA data

Summary:

Aortic valve incompetence is reported as a side effect among people who take Concerta (methylphenidate hydrochloride), especially for people who are female, 30-39 old, have been taking the drug for 2 - 5 years also take Ritalin, and have High blood pressure.

The phase IV clinical study analyzes which people have Aortic valve incompetence when taking Concerta. It is created by eHealthMe based on reports of 20,995 people who have side effects when taking Concerta from the FDA, and is updated regularly.

What is Concerta?

Concerta has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 25,041 Concerta users. Check the latest studies of Concerta.

What is Aortic valve incompetence?

Aortic valve incompetence is found to be associated with 910 drugs and 881 conditions by eHealthMe. Check the latest studies of Aortic valve incompetence.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

20,995 people reported to have side effects when taking Concerta.
Among them, 11 people (0.05%) have Aortic valve incompetence.

Could Concerta cause Aortic valve incompetence?

Among these 11 people:

How long have people been on Concerta when they have Aortic valve incompetence? *

What is the gender of people who have Aortic valve incompetence when taking Concerta? *

female: 90 %
male: 10 %

What is the age of people who have Aortic valve incompetence when taking Concerta? *

What are other drugs people take besides Concerta? *

What are other side effects people have besides Aortic valve incompetence? *

High Blood Pressure: 4 people, 36.36%
Mitral Valve Incompetence (inefficient heart valve): 4 people, 36.36%
Ventricular Hypertrophy (enlargement of ventricles (lower chambers) in the heart): 3 people, 27.27%
Dyspnea Exertional: 3 people, 27.27%
Sinus Arrhythmia (a naturally occurring variation in heart rate that occurs during a breathing cycle): 3 people, 27.27%
Cardiac Valve Disease (heart valve disease): 3 people, 27.27%
Vertebral Foraminal Stenosis (narrowing of the intervertebral foramen): 1 person, 9.09%
Gastritis (inflammation of stomach): 1 person, 9.09%
Ejection Fraction Decreased (systolic heart failure): 1 person, 9.09%
Emotional Distress: 1 person, 9.09%

What are the existing conditions these people have? *

Type 2 Diabetes: 3 people, 27.27%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 3 people, 27.27%
High Blood Pressure: 3 people, 27.27%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 1 person, 9.09%
Metastases To Bone (cancer spreads to bone): 1 person, 9.09%
Conduct Disorder (repetitive and persistent pattern of behaviour by a child or teenager): 1 person, 9.09%
Anaemia (lack of blood): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Concerta and have Aortic valve incompetence?

- Check whether Aortic valve incompetence is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Concerta:

Concerta (25,041 reports)

Browse all side effects of Concerta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aortic valve incompetence:

Aortic valve incompetence (910 drugs)

Browse all the conditions that are associated with Aortic valve incompetence:

Aortic valve incompetence (881 conditions)

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate hydrochloride (the active ingredients of Concerta) and Concerta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.