Concerta and Asthenopia - a phase IV clinical study of FDA data

Summary:

Asthenopia is reported as a side effect among people who take Concerta (methylphenidate hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Lipitor, and have Ill-defined disorder.

The phase IV clinical study analyzes which people have Asthenopia when taking Concerta. It is created by eHealthMe based on reports of 20,995 people who have side effects when taking Concerta from the FDA, and is updated regularly.

What is Concerta?

Concerta has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 25,040 Concerta users. Check the latest studies of Concerta.

What is Asthenopia?

Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem) is found to be associated with 458 drugs and 634 conditions by eHealthMe. Check the latest studies of Asthenopia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

20,995 people reported to have side effects when taking Concerta.
Among them, 16 people (0.08%) have Asthenopia.

Among these 16 people:

How long have people been on Concerta when they have Asthenopia? *

What is the gender of people who have Asthenopia when taking Concerta? *

female: 31.25 %
male: 68.75 %

What is the age of people who have Asthenopia when taking Concerta? *

What are other drugs people take besides Concerta? *

What are other side effects people have besides Asthenopia? *

Fatigue (feeling of tiredness): 11 people, 68.75%
Headache (pain in head): 10 people, 62.50%
Low Density Lipoprotein Increased (cholesterol increased in blood): 8 people, 50.00%
Blindness Unilateral: 8 people, 50.00%
Optic Atrophy (the loss of a proportion of optic disc nerve fibres): 8 people, 50.00%
Optic Ischaemic Neuropathy (optic nerve damage due to lack of blood supply): 8 people, 50.00%
High Blood Cholesterol: 8 people, 50.00%
High Blood Pressure: 8 people, 50.00%
Panic Disorder: 7 people, 43.75%
Stress And Anxiety: 7 people, 43.75%

What are the existing conditions these people have? *

Ill-Defined Disorder: 8 people, 50.00%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 12.50%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 12.50%
Autism Spectrum Disorder (developmental disabilities that can cause significant social, communication and behavioural challenges): 2 people, 12.50%
Skin Wrinkling (wrinkle on skin): 1 person, 6.25%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Concerta and have Asthenopia?

- Check whether Asthenopia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Concerta:

Concerta (25,040 reports)

Asthenopia treatments and more:

Asthenopia (5,947 reports)

Browse all side effects of Concerta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Asthenopia:

Asthenopia (458 drugs)

Browse all the conditions that are associated with Asthenopia:

Asthenopia (634 conditions)

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate hydrochloride (the active ingredients of Concerta) and Concerta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.