Constulose and Headache - a phase IV clinical study of FDA data

Summary:

Headache is reported as a side effect among people who take Constulose (lactulose), especially for people who are male, 50-59 old, also take Hydroxyzine, and have Growth hormone deficiency.

The phase IV clinical study analyzes which people have Headache when taking Constulose. It is created by eHealthMe based on reports of 360 people who have side effects when taking Constulose from the FDA, and is updated regularly.

What is Constulose?

Constulose has active ingredients of lactulose. eHealthMe is studying from 364 Constulose users. Check the latest studies of Constulose.

What is Headache?

Headache (pain in head) is found to be associated with 3,753 drugs and 5,772 conditions by eHealthMe. Check the latest studies of Headache.

On Jul, 14, 2026

360 people reported to have side effects when taking Constulose.
Among them, 18 people (5.0%) have Headache.

Among these 18 people:

What is the gender of people who have Headache when taking Constulose? *

female: 29.41 %
male: 70.59 %

What is the age of people who have Headache when taking Constulose? *

What are other drugs people take besides Constulose? *

What are other side effects people have besides Headache? *

Back Pain: 9 people, 50.00%
Pain: 9 people, 50.00%
Chest Pain: 6 people, 33.33%
Dyspnea (difficult or laboured breathing): 6 people, 33.33%
Skin Blushing/flushing (a sudden reddening of the face, neck): 6 people, 33.33%
Urinary Tract Infection: 6 people, 33.33%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 5 people, 27.78%
Bronchial Obstruction (blockage of the breathing passages to the lungs): 5 people, 27.78%
Blood Pressure Fluctuation: 5 people, 27.78%
Spinal Compression Fracture (fracture due to spinal compression on bone): 5 people, 27.78%

What are the existing conditions these people have? *

Growth Hormone Deficiency: 3 people, 16.67%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 11.11%
Prostate Cancer: 1 person, 5.56%
Overdose: 1 person, 5.56%
Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 1 person, 5.56%
Itching: 1 person, 5.56%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 1 person, 5.56%
Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 1 person, 5.56%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 1 person, 5.56%
Constipation: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Constulose and have Headache?

- Check whether Headache is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Constulose:

Constulose (364 reports)

Headache treatments and more:

Headache (756,642 reports)

Browse all side effects of Constulose:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Headache:

Headache (3,753 drugs)

Browse all the conditions that are associated with Headache:

Headache (5,772 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lactulose (the active ingredients of Constulose) and Constulose (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.