Corlanor and Depression aggravated - a phase IV clinical study of FDA data

Summary:

Depression aggravated is reported as a side effect among people who take Corlanor (ivabradine hydrochloride), especially for people who are female, 30-39 old, also take Promethazine, and have Narcolepsy.

The phase IV clinical study analyzes which people have Depression aggravated when taking Corlanor. It is created by eHealthMe based on reports of 2,372 people who have side effects when taking Corlanor from the FDA, and is updated regularly.

What is Corlanor?

Corlanor has active ingredients of ivabradine hydrochloride. eHealthMe is studying from 2,453 Corlanor users. Check the latest studies of Corlanor.

What is Depression aggravated?

Depression aggravated is found to be associated with 2,390 drugs and 749 conditions by eHealthMe. Check the latest studies of Depression aggravated.

On Jul, 27, 2026

2,372 people reported to have side effects when taking Corlanor.
Among them, 21 people (0.89%) have Depression aggravated.

Could Corlanor cause Depression aggravated?

Among these 21 people:

What is the gender of people who have Depression aggravated when taking Corlanor? *

female: 89.47 %
male: 10.53 %

What is the age of people who have Depression aggravated when taking Corlanor? *

What are other drugs people take besides Corlanor? *

What are other side effects people have besides Depression aggravated? *

Stress And Anxiety: 8 people, 38.10%
Suicidal Ideation: 6 people, 28.57%
Diplopia (double vision): 3 people, 14.29%
Agitation (state of anxiety or nervous excitement): 3 people, 14.29%
Pain: 2 people, 9.52%
Muscle Spasms (muscle contraction): 2 people, 9.52%
Depressed Mood: 2 people, 9.52%
Drug Ineffective: 2 people, 9.52%
Dry Eyes (lack of adequate tears): 2 people, 9.52%
Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 2 people, 9.52%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 38.10%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 23.81%
Sneezing: 2 people, 9.52%
Sleep Paralysis (waking up and unable to move or speak): 2 people, 9.52%
Postural Orthostatic Tachycardia Syndrome (abnormal increase in heart rate on becoming upright): 2 people, 9.52%
Nasopharyngitis (inflammation of the nasopharynx): 2 people, 9.52%
Migraine (headache): 2 people, 9.52%
Drowsiness: 2 people, 9.52%
Systemic Mastocytosis (a condition caused by the accumulation of mast cells in more than one part of the body): 1 person, 4.76%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Corlanor and have Depression aggravated?

- Check whether Depression aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Corlanor:

Corlanor (2,453 reports)

Browse all side effects of Corlanor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Depression aggravated:

Depression aggravated (2,390 drugs)

Browse all the conditions that are associated with Depression aggravated:

Depression aggravated (749 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ivabradine hydrochloride (the active ingredients of Corlanor) and Corlanor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.