Cortef and Bleeding into the skin - a phase IV clinical study of FDA data

Summary:

Bleeding into the skin is reported as a side effect among people who take Cortef (hydrocortisone), especially for people who are female, 60+ old, also take Potassium, and have Polycythaemia vera.

The phase IV clinical study analyzes which people have Bleeding into the skin when taking Cortef. It is created by eHealthMe based on reports of 4,132 people who have side effects when taking Cortef from the FDA, and is updated regularly.

What is Cortef?

Cortef has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 4,254 Cortef users. Check the latest studies of Cortef.

What is Bleeding into the skin?

Bleeding into the skin is found to be associated with 937 drugs and 1,908 conditions by eHealthMe. Check the latest studies of Bleeding into the skin.

On Jul, 09, 2026

4,132 people reported to have side effects when taking Cortef.
Among them, 13 people (0.31%) have Bleeding into the skin.

Could Cortef cause Bleeding into the skin?

Among these 13 people:

What is the gender of people who have Bleeding into the skin when taking Cortef? *

female: 77.78 %
male: 22.22 %

What is the age of people who have Bleeding into the skin when taking Cortef? *

What are other drugs people take besides Cortef? *

What are other side effects people have besides Bleeding into the skin? *

Malaise (a feeling of general discomfort or uneasiness): 9 people, 69.23%
Wheezing (a high-pitched whistling sound made while you breath): 8 people, 61.54%
Muscle Enzyme Increased: 8 people, 61.54%
Muscle Aches (muscle pain): 8 people, 61.54%
Weakness: 8 people, 61.54%
Insomnia (sleeplessness): 8 people, 61.54%
Inflammatory Marker Increased: 8 people, 61.54%
Inflammation: 8 people, 61.54%
Hepatic Enzyme Increased: 8 people, 61.54%
Haematocrit Abnormal: 8 people, 61.54%

What are the existing conditions these people have? *

Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 8 people, 61.54%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 7 people, 53.85%
Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 7 people, 53.85%
Muscle Disorder (muscle disease): 4 people, 30.77%
Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 2 people, 15.38%
Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Cortef and have Bleeding into the skin?

- Check whether Bleeding into the skin is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cortef:

Cortef (4,254 reports)

Browse all side effects of Cortef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bleeding into the skin:

Bleeding into the skin (937 drugs)

Browse all the conditions that are associated with Bleeding into the skin:

Bleeding into the skin (1,908 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone (the active ingredients of Cortef) and Cortef (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.