Cortef and Foot deformity - a phase IV clinical study of FDA data

Summary:

Foot deformity is reported as a side effect among people who take Cortef (hydrocortisone), especially for people who are male, 10-19 old, also take Synthroid, and have Pituitary tumor.

The phase IV clinical study analyzes which people have Foot deformity when taking Cortef. It is created by eHealthMe based on reports of 4,132 people who have side effects when taking Cortef from the FDA, and is updated regularly.

What is Cortef?

Cortef has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 4,254 Cortef users. Check the latest studies of Cortef.

What is Foot deformity?

Foot deformity (functional disability of foot) is found to be associated with 913 drugs and 705 conditions by eHealthMe. Check the latest studies of Foot deformity.

On Jul, 11, 2026

4,132 people reported to have side effects when taking Cortef.
Among them, 42 people (1.02%) have Foot deformity.

Among these 42 people:

What is the gender of people who have Foot deformity when taking Cortef? *

female: 15 %
male: 85 %

What is the age of people who have Foot deformity when taking Cortef? *

What are other drugs people take besides Cortef? *

Synthroid: 38 people, 90.48%
Melatonin: 36 people, 85.71%
Somavert: 36 people, 85.71%
Strattera: 32 people, 76.19%
Carbamazepine: 22 people, 52.38%
Sertraline: 22 people, 52.38%
Primidone: 22 people, 52.38%
Risperidone: 21 people, 50.00%
Propranolol Hydrochloride: 20 people, 47.62%
Sandostatin: 19 people, 45.24%

What are other side effects people have besides Foot deformity? *

Nausea (feeling of having an urge to vomit): 38 people, 90.48%
Constipation: 38 people, 90.48%
Diarrhea: 38 people, 90.48%
Stress And Anxiety: 38 people, 90.48%
Fall: 37 people, 88.10%
Gait Disturbance: 37 people, 88.10%
Nausea And Vomiting: 37 people, 88.10%
The Flu (the flu is caused by an influenza virus): 37 people, 88.10%
Insulin-Like Growth Factor Increased: 36 people, 85.71%
Injection Site Haemorrhage (bleeding from injection site): 36 people, 85.71%

What are the existing conditions these people have? *

Pituitary Tumor: 36 people, 85.71%
Growth Hormone-Producing Pituitary Tumor: 35 people, 83.33%
Constipation: 31 people, 73.81%
Tremor (trembling or shaking movements in one or more parts of your body): 27 people, 64.29%
Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 3 people, 7.14%
Menopausal Symptoms: 2 people, 4.76%
Localised Infection (infection at the single location): 2 people, 4.76%
Hypothalamo-Pituitary Disorder (loss of function in an endocrine gland due to failure of the pituitary gland to secrete hormones which stimulate that gland's function): 2 people, 4.76%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 4.76%
High Blood Pressure: 2 people, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Cortef and have Foot deformity?

- Check whether Foot deformity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cortef:

Cortef (4,254 reports)

Foot deformity treatments and more:

Foot deformity (14,397 reports)

Browse all side effects of Cortef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Foot deformity:

Foot deformity (913 drugs)

Browse all the conditions that are associated with Foot deformity:

Foot deformity (705 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone (the active ingredients of Cortef) and Cortef (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.