Cortenema and Defaecation urgency - a phase IV clinical study of FDA data

Summary:

Defaecation urgency is reported as a side effect among people who take Cortenema (hydrocortisone), especially for people who are male, 40-49 old, also take Mesalamine, and have Ulcerative colitis.

The phase IV clinical study analyzes which people have Defaecation urgency when taking Cortenema. It is created by eHealthMe based on reports of 733 people who have side effects when taking Cortenema from the FDA, and is updated regularly.

What is Cortenema?

Cortenema has active ingredients of hydrocortisone. eHealthMe is studying from 735 Cortenema users. Check the latest studies of Cortenema.

What is Defaecation urgency?

Defaecation urgency (a sudden compelling urge to defecate) is found to be associated with 530 drugs and 518 conditions by eHealthMe. Check the latest studies of Defaecation urgency.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

733 people reported to have side effects when taking Cortenema.
Among them, 20 people (2.73%) have Defaecation urgency.

Could Cortenema cause Defaecation urgency?

Among these 20 people:

What is the gender of people who have Defaecation urgency when taking Cortenema? *

female: 36.84 %
male: 63.16 %

What is the age of people who have Defaecation urgency when taking Cortenema? *

What are other drugs people take besides Cortenema? *

What are other side effects people have besides Defaecation urgency? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 14 people, 70.00%
Haematochezia (passage of stools containing blood): 14 people, 70.00%
Diarrhea: 13 people, 65.00%
Mucous Stools (mucous with stool): 7 people, 35.00%
Abdominal Pain: 7 people, 35.00%
Drug Ineffective: 6 people, 30.00%
Flatulence (flatus expelled through the anus): 3 people, 15.00%
Abnormal Faeces (abnormal stool): 3 people, 15.00%
Rash Erythematous (redness of the skin): 2 people, 10.00%
Poor Venous Access: 2 people, 10.00%

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 20 people, 100.00%
Osteoporosis (bones weak and more likely to break): 2 people, 10.00%
High Blood Cholesterol: 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Cortenema and have Defaecation urgency?

- Check whether Defaecation urgency is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cortenema:

Cortenema (735 reports)

Browse all side effects of Cortenema:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Defaecation urgency:

Defaecation urgency (530 drugs)

Browse all the conditions that are associated with Defaecation urgency:

Defaecation urgency (518 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone (the active ingredients of Cortenema) and Cortenema (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.