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Cosentyx and Weariness - a phase IV clinical study of FDA data

Summary:

Weariness is reported as a side effect among people who take Cosentyx (secukinumab), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Humira, and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people have Weariness when taking Cosentyx. It is created by eHealthMe based on reports of 187,010 people who have side effects when taking Cosentyx from the FDA, and is updated regularly.

What is Cosentyx?

Cosentyx has active ingredients of secukinumab. It is often used in psoriatic arthritis. eHealthMe is studying from 187,244 Cosentyx users. Check the latest studies of Cosentyx.

What is Weariness?

Weariness (physically or mentally exhausted by hard work, exertion, strain) is found to be associated with 5,066 drugs and 6,385 conditions by eHealthMe. Check the latest studies of Weariness.

On Oct, 29, 2025

187,010 people reported to have side effects when taking Cosentyx.
Among them, 12,498 people (6.68%) have Weariness.

Could Cosentyx cause Weariness?

Among these 12,498 people:

How long have people been on Cosentyx when they have Weariness? *

  • < 1 month: 37.5 %
  • 1 - 6 months: 26.5 %
  • 6 - 12 months: 12.33 %
  • 1 - 2 years: 13.83 %
  • 2 - 5 years: 9.67 %
  • 5 - 10 years: 0.17 %
  • 10+ years: 0.0 %

What is the gender of people who have Weariness when taking Cosentyx? *

  • female: 73.77 %
  • male: 26.23 %

What is the age of people who have Weariness when taking Cosentyx? *

  • 0-1: 0.01 %
  • 2-9: 0.01 %
  • 10-19: 0.36 %
  • 20-29: 3.8 %
  • 30-39: 10.87 %
  • 40-49: 30.4 %
  • 50-59: 27.84 %
  • 60+: 26.71 %

What are other drugs people take besides Cosentyx? *

  1. Humira: 3,597 people, 28.78%
  2. Enbrel: 3,392 people, 27.14%
  3. Methotrexate: 3,239 people, 25.92%
  4. Simponi: 3,088 people, 24.71%
  5. Remicade: 2,883 people, 23.07%
  6. Cimzia: 2,844 people, 22.76%
  7. Prednisone: 2,728 people, 21.83%
  8. Orencia: 2,652 people, 21.22%
  9. Arava: 2,614 people, 20.92%
  10. Sulfasalazine: 2,513 people, 20.11%

What are other side effects people have besides Weariness? *

  1. Pain: 5,733 people, 45.87%
  2. Joint Pain: 4,902 people, 39.22%
  3. Drug Ineffective: 4,382 people, 35.06%
  4. Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 3,464 people, 27.72%
  5. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3,256 people, 26.05%
  6. Joint Swelling: 3,240 people, 25.92%
  7. Headache (pain in head): 3,091 people, 24.73%
  8. Malaise (a feeling of general discomfort or uneasiness): 3,055 people, 24.44%
  9. Rashes (redness): 3,023 people, 24.19%
  10. Abdominal Discomfort: 2,719 people, 21.76%

What are the existing conditions these people have? *

  1. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 5,784 people, 46.28%
  2. Psoriasis (immune-mediated disease that affects the skin): 4,347 people, 34.78%
  3. Ankylosing Spondylitis (type of arthritis affecting the spine): 3,073 people, 24.59%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2,848 people, 22.79%
  5. High Blood Pressure: 414 people, 3.31%
  6. Pain: 386 people, 3.09%
  7. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 310 people, 2.48%
  8. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 272 people, 2.18%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 272 people, 2.18%
  10. Stress And Anxiety: 245 people, 1.96%

* Approximation only. Some reports may have incomplete information.

Do you take Cosentyx and have Weariness?

- Check whether Weariness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cosentyx:

Weariness treatments and more:

How severe was Weariness and when was it recovered:

Expand to all the drugs that have ingredients of secukinumab:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Cosentyx side effects:

Browse all side effects of Cosentyx:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Weariness:

Browse all the drugs that are associated with Weariness:

Common conditions associated with Weariness:

Browse all the conditions that are associated with Weariness:

Drugs similar to Cosentyx and Weariness :

How the study uses the data?

The study uses data from the FDA. It is based on secukinumab (the active ingredients of Cosentyx) and Cosentyx (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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