Cosopt and Emphysema - a phase IV clinical study of FDA data

Summary:

Emphysema is reported as a side effect among people who take Cosopt (dorzolamide hydrochloride; timolol maleate), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Spiriva, and have High blood pressure.

The phase IV clinical study analyzes which people have Emphysema when taking Cosopt. It is created by eHealthMe based on reports of 8,872 people who have side effects when taking Cosopt from the FDA, and is updated regularly.

What is Cosopt?

Cosopt has active ingredients of dorzolamide hydrochloride; timolol maleate. It is often used in glaucoma. eHealthMe is studying from 9,029 Cosopt users. Check the latest studies of Cosopt.

What is Emphysema?

Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs) is found to be associated with 1,076 drugs and 1,096 conditions by eHealthMe. Check the latest studies of Emphysema.

On Jul, 15, 2026

8,872 people reported to have side effects when taking Cosopt.
Among them, 12 people (0.14%) have Emphysema.

Among these 12 people:

How long have people been on Cosopt when they have Emphysema? *

What is the gender of people who have Emphysema when taking Cosopt? *

female: 30 %
male: 70 %

What is the age of people who have Emphysema when taking Cosopt? *

What are other drugs people take besides Cosopt? *

Symbicort: 5 people, 41.67%
Prednisone: 5 people, 41.67%
Sertraline Hydrochloride: 5 people, 41.67%
Ventolin: 5 people, 41.67%
Spiriva: 5 people, 41.67%
Xolair: 4 people, 33.33%
Metformin Hydrochloride: 4 people, 33.33%
Travatan: 2 people, 16.67%
Tricor: 1 person, 8.33%
Atacand: 1 person, 8.33%

What are other side effects people have besides Emphysema? *

Asthma: 8 people, 66.67%
Dyspnea (difficult or laboured breathing): 7 people, 58.33%
Dyspnea Exertional: 6 people, 50.00%
Spirometry Abnormal: 5 people, 41.67%
Stress And Anxiety: 5 people, 41.67%
Gastrointestinal Carcinoma (cancer of stomach or intestine): 5 people, 41.67%
Productive Cough: 5 people, 41.67%
Tremor (trembling or shaking movements in one or more parts of your body): 5 people, 41.67%
Weight Increased: 5 people, 41.67%
General Physical Health Deterioration (weak health status): 4 people, 33.33%

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 41.67%
Type 2 Diabetes: 4 people, 33.33%
Stress And Anxiety: 4 people, 33.33%
High Blood Cholesterol: 4 people, 33.33%
Asthma: 4 people, 33.33%
Primary Myelofibrosis (primary disorder of the bone marrow): 1 person, 8.33%
Diabetes: 1 person, 8.33%
Cardiac Failure: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Cosopt and have Emphysema?

- Check whether Emphysema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cosopt:

Cosopt (9,029 reports)

Emphysema treatments and more:

Emphysema (29,685 reports)

How severe was Emphysema and when was it recovered:

Emphysema in Cosopt

Expand to all the drugs that have ingredients of dorzolamide hydrochloride; timolol maleate:

Emphysema and drugs with ingredients of dorzolamide hydrochloride; timolol maleate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cosopt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Emphysema:

Emphysema (1,076 drugs)

Browse all the conditions that are associated with Emphysema:

Emphysema (1,096 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dorzolamide hydrochloride; timolol maleate (the active ingredients of Cosopt) and Cosopt (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.