Cosopt and Eyelid irritation - a phase IV clinical study of FDA data

Summary:

Eyelid irritation is reported as a side effect among people who take Cosopt (dorzolamide hydrochloride; timolol maleate), especially for people who are female, 60+ old, also take Zioptan, and have Dry eyes.

The phase IV clinical study analyzes which people have Eyelid irritation when taking Cosopt. It is created by eHealthMe based on reports of 8,872 people who have side effects when taking Cosopt from the FDA, and is updated regularly.

What is Cosopt?

Cosopt has active ingredients of dorzolamide hydrochloride; timolol maleate. It is often used in glaucoma. eHealthMe is studying from 9,029 Cosopt users. Check the latest studies of Cosopt.

What is Eyelid irritation?

Eyelid irritation is found to be associated with 123 drugs and 233 conditions by eHealthMe. Check the latest studies of Eyelid irritation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

8,872 people reported to have side effects when taking Cosopt.
Among them, 26 people (0.29%) have Eyelid irritation.

Among these 26 people:

What is the gender of people who have Eyelid irritation when taking Cosopt? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Eyelid irritation when taking Cosopt? *

What are other drugs people take besides Cosopt? *

What are other side effects people have besides Eyelid irritation? *

Ocular Hyperaemia (an abnormally large amount of blood in eye): 8 people, 30.77%
Eye Irritation: 8 people, 30.77%
Eye Pruritus (eye itching): 6 people, 23.08%
Eyelids Pruritus (eyelids itching): 6 people, 23.08%
Eyelid Oedema (eyelids are swollen and contain excessive fluid): 4 people, 15.38%
Eyelid Margin Crusting (crusting at the lid margins, generally worse on waking): 4 people, 15.38%
Erythema Of Eyelid (redness of the eyelid): 4 people, 15.38%
Eyelid Skin Dryness: 3 people, 11.54%
Eye Swelling: 2 people, 7.69%
Eyelid Pain: 2 people, 7.69%

What are the existing conditions these people have? *

Normal Tension Glaucoma (a unique condition in which optic nerve damage and vision loss have occurred despite a normal pressure inside the eye): 1 person, 3.85%
Dry Eyes (lack of adequate tears): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Cosopt and have Eyelid irritation?

- Check whether Eyelid irritation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cosopt:

Cosopt (9,029 reports)

Eyelid irritation treatments and more:

Eyelid irritation (2,311 reports)

How severe was Eyelid irritation and when was it recovered:

Eyelid irritation in Cosopt

Expand to all the drugs that have ingredients of dorzolamide hydrochloride; timolol maleate:

Eyelid irritation and drugs with ingredients of dorzolamide hydrochloride; timolol maleate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cosopt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Eyelid irritation:

Eyelid irritation (123 drugs)

Browse all the conditions that are associated with Eyelid irritation:

Eyelid irritation (233 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dorzolamide hydrochloride; timolol maleate (the active ingredients of Cosopt) and Cosopt (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.