Cosopt and Pharyngeal oedema - a phase IV clinical study of FDA data
Summary:
Pharyngeal oedema is reported as a side effect among people who take Cosopt (dorzolamide hydrochloride; timolol maleate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Travatan, and have Chronic lymphocytic leukaemia.
The phase IV clinical study analyzes which people have Pharyngeal oedema when taking Cosopt. It is created by eHealthMe based on reports of 8,872 people who have side effects when taking Cosopt from the FDA, and is updated regularly.
What is Cosopt?
Cosopt has active ingredients of dorzolamide hydrochloride; timolol maleate. It is often used in glaucoma. eHealthMe is studying from 9,029 Cosopt users. Check the latest studies of Cosopt.
What is Pharyngeal oedema?
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal) is found to be associated with 980 drugs and 1,212 conditions by eHealthMe. Check the latest studies of Pharyngeal oedema.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
8,872 people reported to have side effects when taking Cosopt.
Among them, 14 people (0.16%) have Pharyngeal oedema.

Among these 14 people:
How long have people been on Cosopt when they have Pharyngeal oedema? *
- < 1 month: 80 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 20 %
What is the gender of people who have Pharyngeal oedema when taking Cosopt? *
- female: 100 %
- male: 0.0 %
What is the age of people who have Pharyngeal oedema when taking Cosopt? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 16.67 %
- 50-59: 16.67 %
- 60+: 66.67 %
What are other drugs people take besides Cosopt? *
- Travatan: 5 people, 35.71%
- Xalatan: 4 people, 28.57%
- Neurontin: 2 people, 14.29%
- Zometa: 1 person, 7.14%
- Cozaar: 1 person, 7.14%
- Cymbalta: 1 person, 7.14%
- Dexamethasone: 1 person, 7.14%
- Diazepam: 1 person, 7.14%
- Erythromycin: 1 person, 7.14%
- Fentora: 1 person, 7.14%
What are other side effects people have besides Pharyngeal oedema? *
- Dyspnea (difficult or laboured breathing): 5 people, 35.71%
- Swallowing Difficulty: 3 people, 21.43%
- Cough: 3 people, 21.43%
- Drug Hypersensitivity: 3 people, 21.43%
- Vision Blurred: 2 people, 14.29%
- Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 2 people, 14.29%
- Muscle Spasms (muscle contraction): 2 people, 14.29%
- Muscle Aches (muscle pain): 2 people, 14.29%
- Memory Loss: 2 people, 14.29%
- Joint Pain: 2 people, 14.29%
What are the existing conditions these people have? *
- Osteoporosis (bones weak and more likely to break): 1 person, 7.14%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 7.14%
- Neuropathy Peripheral (surface nerve damage): 1 person, 7.14%
- Multiple Myeloma (cancer of the plasma cells): 1 person, 7.14%
- Metastases To Bone (cancer spreads to bone): 1 person, 7.14%
- Intervertebral Disc Disorder (spinal disc disorder): 1 person, 7.14%
- Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 1 person, 7.14%
- High Blood Pressure: 1 person, 7.14%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.14%
- Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Cosopt and have Pharyngeal oedema?
- Check whether Pharyngeal oedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Cosopt:
- Cosopt (9,029 reports)
Pharyngeal oedema treatments and more:
- Pharyngeal oedema (19,077 reports)
How severe was Pharyngeal oedema and when was it recovered:
Expand to all the drugs that have ingredients of dorzolamide hydrochloride; timolol maleate:
- Pharyngeal oedema and drugs with ingredients of dorzolamide hydrochloride; timolol maleate (15 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cosopt:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Pharyngeal oedema:
- Pharyngeal oedema (980 drugs)
Browse all the conditions that are associated with Pharyngeal oedema:
- Pharyngeal oedema (1,212 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on dorzolamide hydrochloride; timolol maleate (the active ingredients of Cosopt) and Cosopt (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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