Cotazym and Death - a phase IV clinical study of FDA data

Summary:

Death is reported as a side effect among people who take Cotazym (pancrelipase (amylase;lipase;protease)), especially for people who are male, 60+ old, also take Dilaudid, and have Carcinoid tumor.

The study is created by eHealthMe based on reports of 373 people who have side effects when taking Cotazym from the FDA, and is updated regularly.

What is Cotazym?

Cotazym has active ingredients of pancrelipase (amylase;lipase;protease). eHealthMe is studying from 377 Cotazym users. Check the latest studies of Cotazym.

On Jul, 15, 2026

373 people reported to have side effects when taking Cotazym.
Among them, 24 people (6.43%) died.

Among these 24 people:

What is the gender of people who died when taking Cotazym? *

female: 33.33 %
male: 66.67 %

What is the age of people who died when taking Cotazym? *

What are other drugs people take besides Cotazym? *

What are other side effects people have before they died? *

Diarrhea: 8 people, 33.33%
Nausea (feeling of having an urge to vomit): 7 people, 29.17%
Nausea And Vomiting: 7 people, 29.17%
Intestinal Obstruction: 7 people, 29.17%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 6 people, 25.00%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 5 people, 20.83%
Hypotension (abnormally low blood pressure): 5 people, 20.83%
High Blood Pressure: 5 people, 20.83%
Weight Decreased: 5 people, 20.83%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 16.67%

What are the existing conditions these people have? *

Carcinoid Tumor: 5 people, 20.83%
Pancreatic Carcinoma (pancreatic cancer): 4 people, 16.67%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 4 people, 16.67%
Back Pain: 3 people, 12.50%
Pain: 3 people, 12.50%
Neuroendocrine Tumor: 3 people, 12.50%
Hepatitis C: 2 people, 8.33%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 2 people, 8.33%
Blood Pressure Abnormal: 2 people, 8.33%
Breakthrough Pain: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cotazym:

Cotazym (377 reports)

Expand to all the drugs that have ingredients of pancrelipase (amylase;lipase;protease):

Death and drugs with ingredients of pancrelipase (amylase;lipase;protease) (1,270 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cotazym:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Death:

Death (3,126 drugs)

Browse all the conditions that are associated with Death:

Death (3,686 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pancrelipase (amylase;lipase;protease) (the active ingredients of Cotazym) and Cotazym (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.