Cotrim and Angina pectoris aggravated - a phase IV clinical study of FDA data

Summary:

Angina pectoris aggravated is reported as a side effect among people who take Cotrim (sulfamethoxazole; trimethoprim), especially for people who are male, 60+ old, also take Amoxicillin, and have Prostatic adenoma.

The phase IV clinical study analyzes which people have Angina pectoris aggravated when taking Cotrim. It is created by eHealthMe based on reports of 8,881 people who have side effects when taking Cotrim from the FDA, and is updated regularly.

What is Cotrim?

Cotrim has active ingredients of sulfamethoxazole; trimethoprim. eHealthMe is studying from 8,890 Cotrim users. Check the latest studies of Cotrim.

What is Angina pectoris aggravated?

Angina pectoris aggravated (chest pain due to ischemia of the heart muscle) is found to be associated with 1,385 drugs and 643 conditions by eHealthMe. Check the latest studies of Angina pectoris aggravated.

On Jul, 04, 2026

8,881 people reported to have side effects when taking Cotrim.
Among them, 11 people (0.12%) have Angina pectoris aggravated.

Could Cotrim cause Angina pectoris aggravated?

Among these 11 people:

What is the gender of people who have Angina pectoris aggravated when taking Cotrim? *

female: 18.18 %
male: 81.82 %

What is the age of people who have Angina pectoris aggravated when taking Cotrim? *

What are other drugs people take besides Cotrim? *

What are other side effects people have besides Angina pectoris aggravated? *

High Blood Pressure: 3 people, 27.27%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 3 people, 27.27%
Rashes (redness): 3 people, 27.27%
Chest Pain: 3 people, 27.27%
Oropharyngeal Pain: 3 people, 27.27%
Diarrhea: 3 people, 27.27%
Fever: 2 people, 18.18%
Cough: 2 people, 18.18%
Fatigue (feeling of tiredness): 2 people, 18.18%
High Blood Cholesterol: 2 people, 18.18%

What are the existing conditions these people have? *

Stomatitis (inflammation of mucous membrane of mouth): 1 person, 9.09%
Hodgkin's Lymphoma (cancer originating from white blood cells): 1 person, 9.09%
Back Pain: 1 person, 9.09%
Computerised Tomogram Abnormal: 1 person, 9.09%
Depression: 1 person, 9.09%
High Blood Cholesterol: 1 person, 9.09%
High Blood Pressure: 1 person, 9.09%
Hiv Infection: 1 person, 9.09%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 9.09%
Prostatic Adenoma (prostatic non-cancerous tumour): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Cotrim and have Angina pectoris aggravated?

- Check whether Angina pectoris aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cotrim:

Cotrim (8,890 reports)

Angina pectoris aggravated treatments and more:

Angina pectoris aggravated (393 reports)

How severe was Angina pectoris aggravated and when was it recovered:

Angina pectoris aggravated in Cotrim

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Angina pectoris aggravated and drugs with ingredients of sulfamethoxazole; trimethoprim (320 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cotrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Angina pectoris aggravated:

Angina pectoris aggravated (1,385 drugs)

Browse all the conditions that are associated with Angina pectoris aggravated:

Angina pectoris aggravated (643 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Cotrim) and Cotrim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.