Cotrim and Cachexia - a phase IV clinical study of FDA data

Summary:

Cachexia is reported as a side effect among people who take Cotrim (sulfamethoxazole; trimethoprim), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Kaletra, and have Hiv infection.

The phase IV clinical study analyzes which people have Cachexia when taking Cotrim. It is created by eHealthMe based on reports of 8,881 people who have side effects when taking Cotrim from the FDA, and is updated regularly.

What is Cotrim?

Cotrim has active ingredients of sulfamethoxazole; trimethoprim. eHealthMe is studying from 8,890 Cotrim users. Check the latest studies of Cotrim.

What is Cachexia?

Cachexia (loss of weight) is found to be associated with 729 drugs and 1,194 conditions by eHealthMe. Check the latest studies of Cachexia.

On Aug, 09, 2025

8,881 people reported to have side effects when taking Cotrim.
Among them, 38 people (0.43%) have Cachexia.

Among these 38 people:

How long have people been on Cotrim when they have Cachexia? *

What is the gender of people who have Cachexia when taking Cotrim? *

female: 63.89 %
male: 36.11 %

What is the age of people who have Cachexia when taking Cotrim? *

What are other drugs people take besides Cotrim? *

What are other side effects people have besides Cachexia? *

General Physical Health Deterioration (weak health status): 15 people, 39.47%
Fever: 14 people, 36.84%
Thrombocytopenia (decrease of platelets in blood): 9 people, 23.68%
Pain: 9 people, 23.68%
Fatigue (feeling of tiredness): 9 people, 23.68%
Anaemia (lack of blood): 9 people, 23.68%
Diarrhea: 8 people, 21.05%
Sepsis (a severe blood infection that can lead to organ failure and death): 8 people, 21.05%
Hair Loss: 8 people, 21.05%
Nausea (feeling of having an urge to vomit): 7 people, 18.42%

What are the existing conditions these people have? *

Hiv Infection: 19 people, 50.00%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 5 people, 13.16%
Multiple Myeloma (cancer of the plasma cells): 3 people, 7.89%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 5.26%
Nausea (feeling of having an urge to vomit): 2 people, 5.26%
Mycobacterial Infection: 2 people, 5.26%
Hiv Infection Cdc Category C3: 2 people, 5.26%
Fungal Infection: 2 people, 5.26%
Erosive Oesophagitis (acid reflux disease can cause tissue damage in the oesophagus over time): 2 people, 5.26%
Drug Dependence: 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Cotrim and have Cachexia?

- Check whether Cachexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cotrim:

Cotrim (8,890 reports)

Cachexia treatments and more:

Cachexia (7,763 reports)

How severe was Cachexia and when was it recovered:

Cachexia in Cotrim

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Cachexia and drugs with ingredients of sulfamethoxazole; trimethoprim (265 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cotrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cachexia:

Cachexia (729 drugs)

Browse all the conditions that are associated with Cachexia:

Cachexia (1,194 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Cotrim) and Cotrim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.