Cotrim and Hypotonia - a phase IV clinical study of FDA data

Summary:

Hypotonia is reported as a side effect among people who take Cotrim (sulfamethoxazole; trimethoprim), especially for people who are male, 50-59 old, have been taking the drug for 1 - 6 months also take Azithromycin, and have Plasmablastic lymphoma.

The phase IV clinical study analyzes which people have Hypotonia when taking Cotrim. It is created by eHealthMe based on reports of 8,881 people who have side effects when taking Cotrim from the FDA, and is updated regularly.

What is Cotrim?

Cotrim has active ingredients of sulfamethoxazole; trimethoprim. eHealthMe is studying from 8,890 Cotrim users. Check the latest studies of Cotrim.

What is Hypotonia?

Hypotonia (low muscle tone) is found to be associated with 835 drugs and 1,766 conditions by eHealthMe. Check the latest studies of Hypotonia.

On Jul, 11, 2026

8,881 people reported to have side effects when taking Cotrim.
Among them, 16 people (0.18%) have Hypotonia.

Among these 16 people:

How long have people been on Cotrim when they have Hypotonia? *

What is the gender of people who have Hypotonia when taking Cotrim? *

female: 37.5 %
male: 62.5 %

What is the age of people who have Hypotonia when taking Cotrim? *

What are other drugs people take besides Cotrim? *

What are other side effects people have besides Hypotonia? *

Cerebral Atrophy (decrement in size of brain): 5 people, 31.25%
Diarrhea: 5 people, 31.25%
Eschar (dead tissue that falls off (sheds) from healthy skin): 5 people, 31.25%
Cough: 5 people, 31.25%
Movement - Uncoordinated: 5 people, 31.25%
Fever: 5 people, 31.25%
Cytomegalovirus Chorioretinitis (infection of choroid and retina of the eye from virus): 5 people, 31.25%
Areflexia (absence of a reflex): 5 people, 31.25%
Febrile Neutropenia (fever with reduced white blood cells): 5 people, 31.25%
Mycobacterium Avium Complex Infection: 5 people, 31.25%

What are the existing conditions these people have? *

Plasmablastic Lymphoma (aggressive b-cell cancer occurring mainly in the jaws and oral cavity): 5 people, 31.25%
Hiv Infection: 4 people, 25.00%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 12.50%
Hiv Test Positive: 2 people, 12.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 12.50%
Pneumonia Pseudomonal (pseudomonas pneumonia is an infection caused by the microbe known as pseudomonas aeruginosa): 1 person, 6.25%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 6.25%
Nausea (feeling of having an urge to vomit): 1 person, 6.25%
Multiple Myeloma (cancer of the plasma cells): 1 person, 6.25%
Gastric Ulcer (stomach ulcer): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Cotrim and have Hypotonia?

- Check whether Hypotonia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cotrim:

Cotrim (8,890 reports)

Hypotonia treatments and more:

Hypotonia (14,614 reports)

How severe was Hypotonia and when was it recovered:

Hypotonia in Cotrim

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Hypotonia and drugs with ingredients of sulfamethoxazole; trimethoprim (182 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cotrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypotonia:

Hypotonia (835 drugs)

Browse all the conditions that are associated with Hypotonia:

Hypotonia (1,766 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Cotrim) and Cotrim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.