Cotrim and Injection site erythema - a phase IV clinical study of FDA data

Summary:

Injection site erythema is reported as a side effect among people who take Cotrim (sulfamethoxazole; trimethoprim), especially for people who are female, 30-39 old, have been taking the drug for 1 - 6 months also take Ibuprofen, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Injection site erythema when taking Cotrim. It is created by eHealthMe based on reports of 8,881 people who have side effects when taking Cotrim from the FDA, and is updated regularly.

What is Cotrim?

Cotrim has active ingredients of sulfamethoxazole; trimethoprim. eHealthMe is studying from 8,890 Cotrim users. Check the latest studies of Cotrim.

What is Injection site erythema?

Injection site erythema (redness at injection site) is found to be associated with 1,464 drugs and 1,417 conditions by eHealthMe. Check the latest studies of Injection site erythema.

On Jul, 05, 2026

8,881 people reported to have side effects when taking Cotrim.
Among them, 17 people (0.19%) have Injection site erythema.

Could Cotrim cause Injection site erythema?

Among these 17 people:

How long have people been on Cotrim when they have Injection site erythema? *

What is the gender of people who have Injection site erythema when taking Cotrim? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Injection site erythema when taking Cotrim? *

What are other drugs people take besides Cotrim? *

Extavia: 7 people, 41.18%
Ibuprofen: 7 people, 41.18%
Allopurinol: 6 people, 35.29%
Omeprazole: 5 people, 29.41%
Quinine Sulfate: 3 people, 17.65%
Ondansetron: 3 people, 17.65%
Piperacillin And Tazobactam: 3 people, 17.65%
Fluconazole: 3 people, 17.65%
Acetaminophen: 3 people, 17.65%
Amoxicillin: 3 people, 17.65%

What are other side effects people have besides Injection site erythema? *

Fever: 10 people, 58.82%
Urinary Tract Infection: 8 people, 47.06%
Diarrhea: 8 people, 47.06%
Headache (pain in head): 7 people, 41.18%
Nausea (feeling of having an urge to vomit): 7 people, 41.18%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 41.18%
Migraine (headache): 7 people, 41.18%
Uterine Cyst: 7 people, 41.18%
Hypoaesthesia (reduced sense of touch or sensation): 7 people, 41.18%
Hot Flush (sudden feelings of heat): 7 people, 41.18%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 41.18%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 3 people, 17.65%
Pain: 3 people, 17.65%
Nausea And Vomiting: 3 people, 17.65%
Muscle Spasms (muscle contraction): 3 people, 17.65%
Lower Respiratory Tract Infection: 3 people, 17.65%
Burkitt Lymphoma (cancer of the lymphatic system): 3 people, 17.65%
Dry Eyes (lack of adequate tears): 3 people, 17.65%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 11.76%
Spinal Compression Fracture (fracture due to spinal compression on bone): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Cotrim and have Injection site erythema?

- Check whether Injection site erythema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cotrim:

Cotrim (8,890 reports)

Injection site erythema treatments and more:

Injection site erythema (120,311 reports)

How severe was Injection site erythema and when was it recovered:

Injection site erythema in Cotrim

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Injection site erythema and drugs with ingredients of sulfamethoxazole; trimethoprim

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cotrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Injection site erythema:

Injection site erythema (1,464 drugs)

Browse all the conditions that are associated with Injection site erythema:

Injection site erythema (1,417 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Cotrim) and Cotrim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.