Cotrim and Obstructive airways disorder - a phase IV clinical study of FDA data

Summary:

Obstructive airways disorder is reported as a side effect among people who take Cotrim (sulfamethoxazole; trimethoprim), especially for people who are male, 40-49 old, have been taking the drug for < 1 month also take Isentress, and have Hiv infection.

The phase IV clinical study analyzes which people have Obstructive airways disorder when taking Cotrim. It is created by eHealthMe based on reports of 8,881 people who have side effects when taking Cotrim from the FDA, and is updated regularly.

What is Cotrim?

Cotrim has active ingredients of sulfamethoxazole; trimethoprim. eHealthMe is studying from 8,890 Cotrim users. Check the latest studies of Cotrim.

What is Obstructive airways disorder?

Obstructive airways disorder (a progressive disease that makes it hard to breathe) is found to be associated with 970 drugs and 1,203 conditions by eHealthMe. Check the latest studies of Obstructive airways disorder.



On Aug, 20, 2025

8,881 people reported to have side effects when taking Cotrim.
Among them, 9 people (0.1%) have Obstructive airways disorder.

Could Cotrim cause Obstructive airways disorder?

Among these 9 people:

How long have people been on Cotrim when they have Obstructive airways disorder? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Obstructive airways disorder when taking Cotrim? *

  • female: 22.22 %
  • male: 77.78 %

What is the age of people who have Obstructive airways disorder when taking Cotrim? *

  • 0-1: 0.0 %
  • 2-9: 12.5 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 50.0 %
  • 50-59: 25.0 %
  • 60+: 12.5 %

What are other drugs people take besides Cotrim? *

  1. Truvada: 4 people, 44.44%
  2. Isentress: 4 people, 44.44%
  3. Ibrutinib: 2 people, 22.22%
  4. Zovirax: 1 person, 11.11%
  5. Konakion: 1 person, 11.11%
  6. Ambisome: 1 person, 11.11%
  7. Bactrim: 1 person, 11.11%
  8. Cellcept: 1 person, 11.11%
  9. Diflucan: 1 person, 11.11%
  10. Edecrin: 1 person, 11.11%

What are other side effects people have besides Obstructive airways disorder? *

  1. Diarrhea: 6 people, 66.67%
  2. Nausea And Vomiting: 6 people, 66.67%
  3. Nausea (feeling of having an urge to vomit): 5 people, 55.56%
  4. Dermatitis Exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss): 4 people, 44.44%
  5. Pruritus Generalised (generalized itching): 4 people, 44.44%
  6. Pneumonitis Chemical (inflammation of the lung caused by aspirating or inhaling irritants): 2 people, 22.22%
  7. White Blood Cell Count Increased: 1 person, 11.11%
  8. Face Oedema (swelling of face): 1 person, 11.11%
  9. Erythema Multiforme (a type of hypersensitivity reaction): 1 person, 11.11%
  10. Enterococcal Infection: 1 person, 11.11%

What are the existing conditions these people have? *

  1. Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 4 people, 44.44%
  2. Hiv Infection: 4 people, 44.44%
  3. High Blood Pressure: 3 people, 33.33%
  4. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 22.22%
  5. Vascular Occlusion (sudden blockage of a blood vessel, usually with a clot): 1 person, 11.11%
  6. Hypoglycemia (low blood sugar): 1 person, 11.11%
  7. Arrhythmias (irregular heartbeat): 1 person, 11.11%
  8. Ascites (accumulation of fluid in the abdominal cavity): 1 person, 11.11%
  9. Breathing Sounds - Abnormal (Stridor): 1 person, 11.11%
  10. Dyspnea (difficult or laboured breathing): 1 person, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Cotrim and have Obstructive airways disorder?

- Check whether Obstructive airways disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cotrim:

Obstructive airways disorder treatments and more:

How severe was Obstructive airways disorder and when was it recovered:

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cotrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Obstructive airways disorder:

Browse all the conditions that are associated with Obstructive airways disorder:


How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Cotrim) and Cotrim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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