Cotrim and Pneumonia aspiration - a phase IV clinical study of FDA data

Summary:

Pneumonia aspiration is reported as a side effect among people who take Cotrim (sulfamethoxazole; trimethoprim), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Prednisolone, and have Immunodeficiency disorders.

The phase IV clinical study analyzes which people have Pneumonia aspiration when taking Cotrim. It is created by eHealthMe based on reports of 8,881 people who have side effects when taking Cotrim from the FDA, and is updated regularly.

What is Cotrim?

Cotrim has active ingredients of sulfamethoxazole; trimethoprim. eHealthMe is studying from 8,890 Cotrim users. Check the latest studies of Cotrim.

What is Pneumonia aspiration?

Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree) is found to be associated with 1,395 drugs and 1,617 conditions by eHealthMe. Check the latest studies of Pneumonia aspiration.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

8,881 people reported to have side effects when taking Cotrim.
Among them, 39 people (0.44%) have Pneumonia aspiration.

Could Cotrim cause Pneumonia aspiration?

Among these 39 people:

How long have people been on Cotrim when they have Pneumonia aspiration? *

What is the gender of people who have Pneumonia aspiration when taking Cotrim? *

female: 16.22 %
male: 83.78 %

What is the age of people who have Pneumonia aspiration when taking Cotrim? *

What are other drugs people take besides Cotrim? *

What are other side effects people have besides Pneumonia aspiration? *

Fatigue (feeling of tiredness): 10 people, 25.64%
Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 8 people, 20.51%
Upper Motor Neurone Lesion (lesion of the neural pathway above the anterior horn cell of the spinal cord or motor nuclei of the cranial nerves): 8 people, 20.51%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 8 people, 20.51%
Hemiparesis (weakness on one side of the body): 8 people, 20.51%
Sepsis (a severe blood infection that can lead to organ failure and death): 6 people, 15.38%
Toxoplasmosis (a parasitic disease caused by the protozoan toxoplasma gondii): 5 people, 12.82%
Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 5 people, 12.82%
Cerebral Toxoplasmosis (parasitic disease of brain caused by the protozoan toxoplasma gondii): 4 people, 10.26%
Acute Kidney Failure: 4 people, 10.26%

What are the existing conditions these people have? *

Immunodeficiency Disorders: 5 people, 12.82%
High Blood Pressure: 4 people, 10.26%
Depression: 4 people, 10.26%
Glioblastoma Multiforme (most common and deadliest of malignant primary brain tumours in adults): 3 people, 7.69%
Cerebral Haemorrhage (bleeding within the brain): 3 people, 7.69%
Cerebral Infarction (less blood supply to brain resulting tissue damage): 3 people, 7.69%
Cholestasis (a condition where bile cannot flow from the liver to the duodenum): 3 people, 7.69%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 3 people, 7.69%
Diabetes: 3 people, 7.69%
Focal Segmental Glomerulosclerosis (scar tissue that forms in parts of the kidney called glomeruli): 3 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Cotrim and have Pneumonia aspiration?

- Check whether Pneumonia aspiration is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cotrim:

Cotrim (8,890 reports)

Pneumonia aspiration treatments and more:

Pneumonia aspiration (30,715 reports)

How severe was Pneumonia aspiration and when was it recovered:

Pneumonia aspiration in Cotrim

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Pneumonia aspiration and drugs with ingredients of sulfamethoxazole; trimethoprim (941 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cotrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pneumonia aspiration:

Pneumonia aspiration (1,395 drugs)

Browse all the conditions that are associated with Pneumonia aspiration:

Pneumonia aspiration (1,617 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Cotrim) and Cotrim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.