Cotrim and Uc - a phase IV clinical study of FDA data

Summary:

Uc is reported as a side effect among people who take Cotrim (sulfamethoxazole; trimethoprim), especially for people who are male, 30-39 old, have been taking the drug for < 1 month also take Pantoprazole, and have Acne.

The phase IV clinical study analyzes which people have Uc when taking Cotrim. It is created by eHealthMe based on reports of 8,881 people who have side effects when taking Cotrim from the FDA, and is updated regularly.

What is Cotrim?

Cotrim has active ingredients of sulfamethoxazole; trimethoprim. eHealthMe is studying from 8,890 Cotrim users. Check the latest studies of Cotrim.

What is Uc?

Uc is found to be associated with 1,309 drugs and 2,020 conditions by eHealthMe. Check the latest studies of Uc.

On Nov, 19, 2025

8,881 people reported to have side effects when taking Cotrim.
Among them, 40 people (0.45%) have Uc.

Among these 40 people:

How long have people been on Cotrim when they have Uc? *

What is the gender of people who have Uc when taking Cotrim? *

female: 22.5 %
male: 77.5 %

What is the age of people who have Uc when taking Cotrim? *

What are other drugs people take besides Cotrim? *

What are other side effects people have besides Uc? *

Weight Decreased: 15 people, 37.50%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 12 people, 30.00%
Nausea (feeling of having an urge to vomit): 12 people, 30.00%
Cytomegalovirus Colitis (an inflammation of the colon from virus): 12 people, 30.00%
Canker Sores (painful, open sore in the mouth): 12 people, 30.00%
Relapsing Fever (bacterial infection characterized by recurring episodes of fever, headache, muscle and joint aches, and nausea): 12 people, 30.00%
Oral Candidiasis (fungal infection of mouth): 12 people, 30.00%
Hypokalemia (low potassium): 12 people, 30.00%
Venous Thrombosis (blood clot (thrombus) that forms within a vein): 12 people, 30.00%
Hepatic Steatosis (fatty liver disease): 11 people, 27.50%

What are the existing conditions these people have? *

Acne (skin problems that cause pimples): 7 people, 17.50%
Stress And Anxiety: 4 people, 10.00%
Cytomegalovirus Test Positive: 4 people, 10.00%
Iron Deficiency: 3 people, 7.50%
Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 2 people, 5.00%
Parkinson's Disease: 2 people, 5.00%
High Blood Pressure: 2 people, 5.00%
Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 5.00%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 5.00%
Pancreatitis (inflammation of pancreas): 1 person, 2.50%

* Approximation only. Some reports may have incomplete information.

Do you take Cotrim and have Uc?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cotrim:

Cotrim (8,890 reports)

Uc treatments and more:

Uc (188,231 reports)

How severe was Uc and when was it recovered:

Uc in Cotrim

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Uc and drugs with ingredients of sulfamethoxazole; trimethoprim (772 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cotrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Uc:

Uc (1,309 drugs)

Browse all the conditions that are associated with Uc:

Uc (2,020 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Cotrim) and Cotrim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.