Coumadin and Enzyme abnormality - a phase IV clinical study of FDA data

Summary:

Enzyme abnormality is reported as a side effect among people who take Coumadin (warfarin sodium), especially for people who are male, 60+ old, also take Synthroid, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Enzyme abnormality when taking Coumadin. It is created by eHealthMe based on reports of 128,882 people who have side effects when taking Coumadin from the FDA, and is updated regularly.

What is Coumadin?

Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. eHealthMe is studying from 133,228 Coumadin users. Check the latest studies of Coumadin.

What is Enzyme abnormality?

Enzyme abnormality is found to be associated with 112 drugs and 336 conditions by eHealthMe. Check the latest studies of Enzyme abnormality.

On Jul, 13, 2026

128,882 people reported to have side effects when taking Coumadin.
Among them, 14 people (0.01%) have Enzyme abnormality.

Could Coumadin cause Enzyme abnormality?

Among these 14 people:

What is the gender of people who have Enzyme abnormality when taking Coumadin? *

female: 50 %
male: 50 %

What is the age of people who have Enzyme abnormality when taking Coumadin? *

What are other drugs people take besides Coumadin? *

What are other side effects people have besides Enzyme abnormality? *

Weakness: 6 people, 42.86%
Head Injury: 5 people, 35.71%
Weight Increased: 3 people, 21.43%
Muscle Swelling: 3 people, 21.43%
Agitation (state of anxiety or nervous excitement): 3 people, 21.43%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 3 people, 21.43%
Dizziness: 3 people, 21.43%
Drug Ineffective: 3 people, 21.43%
Dyspnea (difficult or laboured breathing): 3 people, 21.43%
Fall: 3 people, 21.43%

What are the existing conditions these people have? *

High Blood Cholesterol: 6 people, 42.86%
Diabetes: 4 people, 28.57%
Pain In Extremity: 3 people, 21.43%
Ill-Defined Disorder: 3 people, 21.43%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 21.43%
Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium): 3 people, 21.43%
Cardiac Failure Congestive: 3 people, 21.43%
Cardiac Disorder: 3 people, 21.43%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 14.29%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Coumadin and have Enzyme abnormality?

- Check whether Enzyme abnormality is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Coumadin:

Coumadin (133,228 reports)

Browse all side effects of Coumadin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Enzyme abnormality:

Enzyme abnormality (112 drugs)

Browse all the conditions that are associated with Enzyme abnormality:

Enzyme abnormality (336 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on warfarin sodium (the active ingredients of Coumadin) and Coumadin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.