Coumadin and Eyelid margin crusting - a phase IV clinical study of FDA data

Summary:

Eyelid margin crusting is reported as a side effect among people who take Coumadin (warfarin sodium), especially for people who are male, 40-49 old, also take Elidel, and have Eczema.

The phase IV clinical study analyzes which people have Eyelid margin crusting when taking Coumadin. It is created by eHealthMe based on reports of 128,882 people who have side effects when taking Coumadin from the FDA, and is updated regularly.

What is Coumadin?

Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. eHealthMe is studying from 133,228 Coumadin users. Check the latest studies of Coumadin.

What is Eyelid margin crusting?

Eyelid margin crusting (crusting at the lid margins, generally worse on waking) is found to be associated with 196 drugs and 279 conditions by eHealthMe. Check the latest studies of Eyelid margin crusting.



On Jul, 09, 2026

128,882 people reported to have side effects when taking Coumadin.
Among them, 20 people (0.02%) have Eyelid margin crusting.

Could Coumadin cause Eyelid margin crusting?

Among these 20 people:

What is the gender of people who have Eyelid margin crusting when taking Coumadin? *

  • female: 45 %
  • male: 55 %

What is the age of people who have Eyelid margin crusting when taking Coumadin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 64.71 %
  • 50-59: 5.88 %
  • 60+: 29.41 %

What are other drugs people take besides Coumadin? *

  1. Ativan: 10 people, 50.00%
  2. Elidel: 10 people, 50.00%
  3. Ventolin: 9 people, 45.00%
  4. Flonase: 9 people, 45.00%
  5. Hydroxyzine: 9 people, 45.00%
  6. Ibuprofen: 9 people, 45.00%
  7. Pepcid: 9 people, 45.00%
  8. Ranitidine: 9 people, 45.00%
  9. Depo-Medrol: 9 people, 45.00%
  10. Restoril: 8 people, 40.00%

What are other side effects people have besides Eyelid margin crusting? *

  1. Pain: 14 people, 70.00%
  2. Fatigue (feeling of tiredness): 13 people, 65.00%
  3. Dyspnea (difficult or laboured breathing): 12 people, 60.00%
  4. Stomatitis (inflammation of mucous membrane of mouth): 12 people, 60.00%
  5. Cough: 11 people, 55.00%
  6. Dry Eyes (lack of adequate tears): 11 people, 55.00%
  7. Blood Glucose Increased: 10 people, 50.00%
  8. Insomnia (sleeplessness): 10 people, 50.00%
  9. Eye Pain: 10 people, 50.00%
  10. Nausea And Vomiting: 10 people, 50.00%

What are the existing conditions these people have? *

  1. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 9 people, 45.00%
  2. Thrombosis (formation of a blood clot inside a blood vessel): 3 people, 15.00%
  3. Renal Cell Carcinoma (a kidney cancer): 2 people, 10.00%
  4. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 10.00%
  5. Renal Cancer Metastatic (cancer of kidney spreads to other part): 1 person, 5.00%
  6. Otorrhea (discharge from the ear): 1 person, 5.00%
  7. Mycosis Fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin): 1 person, 5.00%
  8. Herpes Zoster: 1 person, 5.00%
  9. Glaucoma (increased fluid pressure in the eye with vision loss): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Coumadin and have Eyelid margin crusting?

- Check whether Eyelid margin crusting is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Coumadin:

Eyelid margin crusting treatments and more:

How severe was Eyelid margin crusting and when was it recovered:

Expand to all the drugs that have ingredients of warfarin sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Coumadin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Eyelid margin crusting:

Browse all the conditions that are associated with Eyelid margin crusting:


How the study uses the data?

The study uses data from the FDA. It is based on warfarin sodium (the active ingredients of Coumadin) and Coumadin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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