Coumadin and Rheumatic fever - a phase IV clinical study of FDA data

Summary:

Rheumatic fever is reported as a side effect among people who take Coumadin (warfarin sodium), especially for people who are female, 60+ old, also take Furosemide, and have High blood pressure.

The phase IV clinical study analyzes which people have Rheumatic fever when taking Coumadin. It is created by eHealthMe based on reports of 128,882 people who have side effects when taking Coumadin from the FDA, and is updated regularly.

What is Coumadin?

Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. eHealthMe is studying from 133,228 Coumadin users. Check the latest studies of Coumadin.

What is Rheumatic fever?

Rheumatic fever (an inflammatory disease that occurs following a streptococcus pyogenes infection) is found to be associated with 264 drugs and 236 conditions by eHealthMe. Check the latest studies of Rheumatic fever.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

128,882 people reported to have side effects when taking Coumadin.
Among them, 22 people (0.02%) have Rheumatic fever.

Among these 22 people:

What is the gender of people who have Rheumatic fever when taking Coumadin? *

female: 90.91 %
male: 9.09 %

What is the age of people who have Rheumatic fever when taking Coumadin? *

What are other drugs people take besides Coumadin? *

What are other side effects people have besides Rheumatic fever? *

Dyspnea (difficult or laboured breathing): 20 people, 90.91%
Atherosclerosis (disorder of the arteries): 19 people, 86.36%
Pain: 19 people, 86.36%
High Blood Pressure: 19 people, 86.36%
Stress And Anxiety: 18 people, 81.82%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 18 people, 81.82%
Cataract (clouding of the lens inside the eye): 18 people, 81.82%
Deformity (disfigurement): 17 people, 77.27%
Exposed Bone In Jaw: 17 people, 77.27%
Tricuspid Valve Incompetence (inefficient heart valve): 17 people, 77.27%

What are the existing conditions these people have? *

Osteomyelitis (infection of bone): 10 people, 45.45%
Depression: 10 people, 45.45%
Dyspnea (difficult or laboured breathing): 10 people, 45.45%
High Blood Pressure: 10 people, 45.45%
Breast Cancer Metastatic: 7 people, 31.82%
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 5 people, 22.73%
Osteoporosis (bones weak and more likely to break): 5 people, 22.73%
Heart Rate Irregular: 1 person, 4.55%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 4.55%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Coumadin and have Rheumatic fever?

- Check whether Rheumatic fever is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Coumadin:

Coumadin (133,228 reports)

Rheumatic fever treatments and more:

Rheumatic fever (3,414 reports)

Browse all side effects of Coumadin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rheumatic fever:

Rheumatic fever (264 drugs)

Browse all the conditions that are associated with Rheumatic fever:

Rheumatic fever (236 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on warfarin sodium (the active ingredients of Coumadin) and Coumadin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.