Cozaar and Lupus nephritis - a phase IV clinical study of FDA data

Summary:

Lupus nephritis is reported as a side effect among people who take Cozaar (losartan potassium), especially for people who are female, 50-59 old, also take Aranesp, and have Cryoglobulinaemia.

The phase IV clinical study analyzes which people have Lupus nephritis when taking Cozaar. It is created by eHealthMe based on reports of 43,582 people who have side effects when taking Cozaar from the FDA, and is updated regularly.

What is Cozaar?

Cozaar has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 45,124 Cozaar users. Check the latest studies of Cozaar.

What is Lupus nephritis?

Lupus nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue) is found to be associated with 166 drugs and 372 conditions by eHealthMe. Check the latest studies of Lupus nephritis.

On Aug, 05, 2026

43,582 people reported to have side effects when taking Cozaar.
Among them, 13 people (0.03%) have Lupus nephritis.

Among these 13 people:

What is the gender of people who have Lupus nephritis when taking Cozaar? *

female: 90 %
male: 10 %

What is the age of people who have Lupus nephritis when taking Cozaar? *

What are other drugs people take besides Cozaar? *

What are other side effects people have besides Lupus nephritis? *

Nausea And Vomiting: 10 people, 76.92%
Abdominal Pain Upper: 9 people, 69.23%
Drug Ineffective: 9 people, 69.23%
Headache (pain in head): 9 people, 69.23%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 9 people, 69.23%
Hypotension (abnormally low blood pressure): 9 people, 69.23%
Insomnia (sleeplessness): 9 people, 69.23%
Laboratory Test Abnormal: 9 people, 69.23%
Malaise (a feeling of general discomfort or uneasiness): 9 people, 69.23%
Blood Pressure Diastolic Decreased: 5 people, 38.46%

What are the existing conditions these people have? *

Vasculitis (inflammation of a blood vessel or blood vessels): 9 people, 69.23%
Cryoglobulinaemia (blood contains large amounts of cryoglobulins - proteins): 9 people, 69.23%
Osteoporosis (bones weak and more likely to break): 2 people, 15.38%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 15.38%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 7.69%
Reiter's Syndrome (a type of reactive arthritis, it happens as a reaction to a bacterial infection): 1 person, 7.69%
Oedema (fluid collection in tissue): 1 person, 7.69%
Muscle Spasms (muscle contraction): 1 person, 7.69%
Gastritis (inflammation of stomach): 1 person, 7.69%
Diabetes: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Cozaar and have Lupus nephritis?

- Check whether Lupus nephritis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cozaar:

Cozaar (45,124 reports)

Lupus nephritis treatments and more:

Lupus nephritis (10,611 reports)

Browse all side effects of Cozaar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lupus nephritis:

Lupus nephritis (166 drugs)

Browse all the conditions that are associated with Lupus nephritis:

Lupus nephritis (372 conditions)

Related publications that referenced our studies

Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on losartan potassium (the active ingredients of Cozaar) and Cozaar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.