Cozaar and Tendon rupture - a phase IV clinical study of FDA data

Summary:

Tendon rupture is reported as a side effect among people who take Cozaar (losartan potassium), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Levaquin, and have Osteoporosis.

The phase IV clinical study analyzes which people have Tendon rupture when taking Cozaar. It is created by eHealthMe based on reports of 43,582 people who have side effects when taking Cozaar from the FDA, and is updated regularly.

What is Cozaar?

Cozaar has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 45,124 Cozaar users. Check the latest studies of Cozaar.

What is Tendon rupture?

Tendon rupture (tear of tendon) is found to be associated with 805 drugs and 1,060 conditions by eHealthMe. Check the latest studies of Tendon rupture.



On Jul, 11, 2026

43,582 people reported to have side effects when taking Cozaar.
Among them, 48 people (0.11%) have Tendon rupture.

Could Cozaar cause Tendon rupture?

Among these 48 people:

How long have people been on Cozaar when they have Tendon rupture? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 50 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Tendon rupture when taking Cozaar? *

  • female: 36.17 %
  • male: 63.83 %

What is the age of people who have Tendon rupture when taking Cozaar? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 2.63 %
  • 50-59: 7.89 %
  • 60+: 89.47 %

What are other drugs people take besides Cozaar? *

  1. Lipitor: 13 people, 27.08%
  2. Levaquin: 13 people, 27.08%
  3. Fosamax: 10 people, 20.83%
  4. Hytrin: 8 people, 16.67%
  5. Proscar: 8 people, 16.67%
  6. Cardura: 7 people, 14.58%
  7. Norvasc: 6 people, 12.50%
  8. Hydrochlorothiazide: 5 people, 10.42%
  9. Aspirin: 5 people, 10.42%
  10. Synthroid: 5 people, 10.42%

What are other side effects people have besides Tendon rupture? *

  1. Fall: 11 people, 22.92%
  2. Gastritis (inflammation of stomach): 10 people, 20.83%
  3. Hypoaesthesia (reduced sense of touch or sensation): 10 people, 20.83%
  4. Femur Fracture: 10 people, 20.83%
  5. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 10 people, 20.83%
  6. Nausea (feeling of having an urge to vomit): 9 people, 18.75%
  7. Depression: 9 people, 18.75%
  8. Tendonitis (a condition that causes pain and swelling of tendons): 9 people, 18.75%
  9. Diarrhea: 8 people, 16.67%
  10. Dizziness: 8 people, 16.67%

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 10 people, 20.83%
  2. Enlarged Prostate: 7 people, 14.58%
  3. Asthma: 5 people, 10.42%
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 5 people, 10.42%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 8.33%
  6. Urinary Tract Infection: 3 people, 6.25%
  7. Stress And Anxiety: 3 people, 6.25%
  8. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 6.25%
  9. High Blood Cholesterol: 3 people, 6.25%
  10. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Cozaar and have Tendon rupture?

- Check whether Tendon rupture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cozaar:

Tendon rupture treatments and more:

How severe was Tendon rupture and when was it recovered:

Expand to all the drugs that have ingredients of losartan potassium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cozaar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tendon rupture:

Browse all the conditions that are associated with Tendon rupture:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on losartan potassium (the active ingredients of Cozaar) and Cozaar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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