Crixivan and Ankle fracture - a phase IV clinical study of FDA data

Summary:

Ankle fracture is reported as a side effect among people who take Crixivan (indinavir sulfate), especially for people who are male, 40-49 old, also take Norvir, and have Hiv infection.

The phase IV clinical study analyzes which people have Ankle fracture when taking Crixivan. It is created by eHealthMe based on reports of 6,310 people who have side effects when taking Crixivan from the FDA, and is updated regularly.

What is Crixivan?

Crixivan has active ingredients of indinavir sulfate. eHealthMe is studying from 6,312 Crixivan users. Check the latest studies of Crixivan.

What is Ankle fracture?

Ankle fracture is found to be associated with 1,115 drugs and 1,050 conditions by eHealthMe. Check the latest studies of Ankle fracture.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

6,310 people reported to have side effects when taking Crixivan.
Among them, 16 people (0.25%) have Ankle fracture.

$Could Crixivan cause Ankle fracture?$

Among these 16 people:

What is the gender of people who have Ankle fracture when taking Crixivan? *

female: 6.25 %
male: 93.75 %

What is the age of people who have Ankle fracture when taking Crixivan? *

What are other drugs people take besides Crixivan? *

What are other side effects people have besides Ankle fracture? *

Stress And Anxiety: 16 people, 100.00%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 16 people, 100.00%
Emotional Distress: 16 people, 100.00%
Pain: 16 people, 100.00%
Osteoporosis (bones weak and more likely to break): 13 people, 81.25%
Bone Density Decreased: 8 people, 50.00%
Renal Impairment (severely reduced kidney function): 7 people, 43.75%
Osteopenia (a condition where bone mineral density is lower than normal): 7 people, 43.75%
Joint Pain: 6 people, 37.50%
Depression: 6 people, 37.50%

What are the existing conditions these people have? *

Hiv Infection: 16 people, 100.00%
Viral Infection: 4 people, 25.00%
Stress And Anxiety: 4 people, 25.00%
Quit Smoking: 4 people, 25.00%
Pain: 4 people, 25.00%
Nausea (feeling of having an urge to vomit): 4 people, 25.00%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 25.00%
High Blood Cholesterol: 4 people, 25.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 25.00%
Depression: 4 people, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Crixivan and have Ankle fracture?

- Check whether Ankle fracture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Crixivan:

Crixivan (6,312 reports)

Ankle fracture treatments and more:

Ankle fracture (20,557 reports)

Browse all side effects of Crixivan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ankle fracture:

Ankle fracture (1,115 drugs)

Browse all the conditions that are associated with Ankle fracture:

Ankle fracture (1,050 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on indinavir sulfate (the active ingredients of Crixivan) and Crixivan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.