Crysvita and Foot deformity - a phase IV clinical study of FDA data

Summary:

Foot deformity is reported as a side effect among people who take Crysvita (burosumab-twza), especially for people who are also take Advil, and have Phosphorus metabolism disorder.

The phase IV clinical study analyzes which people have Foot deformity when taking Crysvita. It is created by eHealthMe based on reports of 6,746 people who have side effects when taking Crysvita from the FDA, and is updated regularly.

What is Crysvita?

Crysvita has active ingredients of burosumab-twza. eHealthMe is studying from 6,746 Crysvita users. Check the latest studies of Crysvita.

What is Foot deformity?

Foot deformity (functional disability of foot) is found to be associated with 912 drugs and 706 conditions by eHealthMe. Check the latest studies of Foot deformity.

On Aug, 02, 2026

6,746 people reported to have side effects when taking Crysvita.
Among them, 17 people (0.25%) have Foot deformity.

Among these 17 people:

What are other drugs people take besides Crysvita? *

Tylenol: 1 person, 5.88%
Skytrofa: 1 person, 5.88%
Oxycodone: 1 person, 5.88%
Albuterol Sulfate: 1 person, 5.88%
Advil: 1 person, 5.88%

What are other side effects people have besides Foot deformity? *

Knee Deformity (functional disability of knee): 8 people, 47.06%
Joint Pain: 6 people, 35.29%
Blood Phosphorus Decreased: 5 people, 29.41%
Pain In Extremity: 4 people, 23.53%
Body Height Below Normal: 4 people, 23.53%
Gait Disturbance: 4 people, 23.53%
Rickets (softening of bones): 3 people, 17.65%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 3 people, 17.65%
Dental Caries: 3 people, 17.65%
Tooth Abscess (pus formation in tooth): 3 people, 17.65%

What are the existing conditions these people have? *

Phosphorus Metabolism Disorder: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Crysvita and have Foot deformity?

- Check whether Foot deformity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Crysvita:

Crysvita (6,746 reports)

Foot deformity treatments and more:

Foot deformity (14,397 reports)

Browse all side effects of Crysvita:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Foot deformity:

Foot deformity (912 drugs)

Browse all the conditions that are associated with Foot deformity:

Foot deformity (706 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on burosumab-twza (the active ingredients of Crysvita) and Crysvita (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.