Cyanocobalamin and Aphonia - a phase IV clinical study of FDA data

Summary:

Aphonia is reported as a side effect among people who take Cyanocobalamin (cyanocobalamin), especially for people who are female, 60+ old, also take Vitamin C, and have Pemphigus.

The phase IV clinical study analyzes which people have Aphonia when taking Cyanocobalamin. It is created by eHealthMe based on reports of 14,464 people who have side effects when taking Cyanocobalamin from the FDA, and is updated regularly.

What is Cyanocobalamin?

Cyanocobalamin has active ingredients of cyanocobalamin. It is often used in vitamin b12 deficiency. eHealthMe is studying from 14,651 Cyanocobalamin users. Check the latest studies of Cyanocobalamin.

What is Aphonia?

Aphonia (inability to produce voice) is found to be associated with 884 drugs and 848 conditions by eHealthMe. Check the latest studies of Aphonia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 17, 2026

14,464 people reported to have side effects when taking Cyanocobalamin.
Among them, 24 people (0.17%) have Aphonia.

Among these 24 people:

What is the gender of people who have Aphonia when taking Cyanocobalamin? *

female: 90 %
male: 10 %

What is the age of people who have Aphonia when taking Cyanocobalamin? *

What are other drugs people take besides Cyanocobalamin? *

What are other side effects people have besides Aphonia? *

Swallowing Difficulty: 12 people, 50.00%
Weight Increased: 10 people, 41.67%
Discomfort: 10 people, 41.67%
Oral Mucosa Erosion (erosion of mouth mucous membrane): 9 people, 37.50%
Lip Erosion (peeling off of lip): 9 people, 37.50%
Oral Disorder (mouth disease): 9 people, 37.50%
Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters): 9 people, 37.50%
Epiglottic Oedema (swelling and inflammation of the epiglottis): 9 people, 37.50%
Epiglottic Erythema (presence of supraglottic oedema in larynx): 9 people, 37.50%
Swallowing Pain Or Burning: 9 people, 37.50%

What are the existing conditions these people have? *

Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters): 9 people, 37.50%
Agitation (state of anxiety or nervous excitement): 3 people, 12.50%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 12.50%
Bowel Movement Irregularity: 3 people, 12.50%
Pain: 3 people, 12.50%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 12.50%
Freezing Phenomenon: 2 people, 8.33%
Renal Cell Carcinoma (a kidney cancer): 2 people, 8.33%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 2 people, 8.33%
Parkinson's Disease: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Cyanocobalamin and have Aphonia?

- Check whether Aphonia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cyanocobalamin:

Cyanocobalamin (14,651 reports)

Aphonia treatments and more:

Aphonia (15,979 reports)

Browse all side effects of Cyanocobalamin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aphonia:

Aphonia (884 drugs)

Browse all the conditions that are associated with Aphonia:

Aphonia (848 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cyanocobalamin (the active ingredients of Cyanocobalamin) and Cyanocobalamin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.