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Cyclophosphamide and Enterobacter sepsis - a phase IV clinical study of FDA data

Summary:

Enterobacter sepsis is reported as a side effect among people who take Cyclophosphamide (cyclophosphamide), especially for people who are male, 30-39 old, have been taking the drug for < 1 month also take Methotrexate, and have Central nervous system lymphoma.

The phase IV clinical study analyzes which people have Enterobacter sepsis when taking Cyclophosphamide. It is created by eHealthMe based on reports of 185,094 people who have side effects when taking Cyclophosphamide from the FDA, and is updated regularly.

What is Cyclophosphamide?

Cyclophosphamide has active ingredients of cyclophosphamide. It is often used in multiple myeloma. eHealthMe is studying from 185,240 Cyclophosphamide users. Check the latest studies of Cyclophosphamide.

What is Enterobacter sepsis?

Enterobacter sepsis (sepsis due to bacteria of the family enterobacteriaceae) is found to be associated with 75 drugs and 217 conditions by eHealthMe. Check the latest studies of Enterobacter sepsis.

On Jul, 08, 2026

185,094 people reported to have side effects when taking Cyclophosphamide.
Among them, 45 people (0.02%) have Enterobacter sepsis.

Could Cyclophosphamide cause Enterobacter sepsis?

Among these 45 people:

How long have people been on Cyclophosphamide when they have Enterobacter sepsis? *

  • < 1 month: 60 %
  • 1 - 6 months: 40 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Enterobacter sepsis when taking Cyclophosphamide? *

  • female: 17.5 %
  • male: 82.5 %

What is the age of people who have Enterobacter sepsis when taking Cyclophosphamide? *

  • 0-1: 8.82 %
  • 2-9: 5.88 %
  • 10-19: 2.94 %
  • 20-29: 11.76 %
  • 30-39: 44.12 %
  • 40-49: 8.82 %
  • 50-59: 5.88 %
  • 60+: 11.76 %

What are other drugs people take besides Cyclophosphamide? *

  1. Methotrexate: 18 people, 40.00%
  2. Cytarabine: 15 people, 33.33%
  3. Busulfan: 14 people, 31.11%
  4. Thiotepa: 14 people, 31.11%
  5. Dexamethasone: 13 people, 28.89%
  6. Ceftazidime: 10 people, 22.22%
  7. Ifosfamide: 10 people, 22.22%
  8. Fludarabine Phosphate: 7 people, 15.56%
  9. Mycophenolate Mofetil: 6 people, 13.33%
  10. Tacrolimus: 5 people, 11.11%

What are other side effects people have besides Enterobacter sepsis? *

  1. Pseudomonal Sepsis (pseudomonas infections are diseases caused by a bacterium from the genus pseudomonas): 15 people, 33.33%
  2. Mucosal Inflammation (infection of mucous membrane): 15 people, 33.33%
  3. Acute Kidney Failure: 6 people, 13.33%
  4. Fever: 6 people, 13.33%
  5. Drug Ineffective: 4 people, 8.89%
  6. Hypotension (abnormally low blood pressure): 4 people, 8.89%
  7. Engraft Failure: 4 people, 8.89%
  8. Febrile Neutropenia (fever with reduced white blood cells): 4 people, 8.89%
  9. Respiratory Rate Increased (excess breathing rate/min): 4 people, 8.89%
  10. Gastritis Erosive (a break in the surface layer of the membrane lining the stomach with infection): 3 people, 6.67%

What are the existing conditions these people have? *

  1. Central Nervous System Lymphoma (cancer of central nervous system forms in lymph tissue): 14 people, 31.11%
  2. Bone Marrow Conditioning Regimen: 8 people, 17.78%
  3. Hepatosplenic T-Cell Lymphoma (neoplasm comprising medium-sized cytotoxic t-cells that show a significant sinusoidal infiltration in the liver, spleen, and bone marrow): 6 people, 13.33%
  4. High Blood Pressure: 3 people, 6.67%
  5. Oedema Peripheral (superficial swelling): 3 people, 6.67%
  6. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 4.44%
  7. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 1 person, 2.22%
  8. B Precursor Type Acute Leukaemia (lymphoid cancer): 1 person, 2.22%
  9. Haematopoietic Stem Cell Mobilisation: 1 person, 2.22%
  10. T-Cell Lymphoma (a blood cell cancer): 1 person, 2.22%

* Approximation only. Some reports may have incomplete information.

Do you take Cyclophosphamide and have Enterobacter sepsis?

- Check whether Enterobacter sepsis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cyclophosphamide:

Enterobacter sepsis treatments and more:

How severe was Enterobacter sepsis and when was it recovered:

Expand to all the drugs that have ingredients of cyclophosphamide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cyclophosphamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Enterobacter sepsis:

Browse all the conditions that are associated with Enterobacter sepsis:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on cyclophosphamide (the active ingredients of Cyclophosphamide) and Cyclophosphamide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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