Cyclosporine and Knee deformity - a phase IV clinical study of FDA data

Summary:

Knee deformity is reported as a side effect among people who take Cyclosporine (cyclosporine), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Cosentyx, and have Aplastic anemia.

The phase IV clinical study analyzes which people have Knee deformity when taking Cyclosporine. It is created by eHealthMe based on reports of 58,335 people who have side effects when taking Cyclosporine from the FDA, and is updated regularly.

What is Cyclosporine?

Cyclosporine has active ingredients of cyclosporine. It is often used in psoriasis. eHealthMe is studying from 58,714 Cyclosporine users. Check the latest studies of Cyclosporine.

What is Knee deformity?

Knee deformity (functional disability of knee) is found to be associated with 189 drugs and 107 conditions by eHealthMe. Check the latest studies of Knee deformity.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

58,335 people reported to have side effects when taking Cyclosporine.
Among them, 17 people (0.03%) have Knee deformity.

Could Cyclosporine cause Knee deformity?

Among these 17 people:

How long have people been on Cyclosporine when they have Knee deformity? *

What is the gender of people who have Knee deformity when taking Cyclosporine? *

female: 23.53 %
male: 76.47 %

What is the age of people who have Knee deformity when taking Cyclosporine? *

What are other drugs people take besides Cyclosporine? *

What are other side effects people have besides Knee deformity? *

Malaise (a feeling of general discomfort or uneasiness): 8 people, 47.06%
Hypokinesia (decreased bodily movement): 7 people, 41.18%
Joint Stiffness: 7 people, 41.18%
Thrombosis (formation of a blood clot inside a blood vessel): 7 people, 41.18%
Fluid Retention (an abnormal accumulation of fluid in the blood): 7 people, 41.18%
Arthropathy: 7 people, 41.18%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 7 people, 41.18%
Skin Disorder (skin disease): 6 people, 35.29%
Dermatitis Exfoliative Generalised (inflammatory skin disease with erythema and scaling that affects nearly the entire cutaneous surface): 6 people, 35.29%
Joint Pain: 5 people, 29.41%

What are the existing conditions these people have? *

Aplastic Anemia: 3 people, 17.65%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.88%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 5.88%
Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 1 person, 5.88%
Itching: 1 person, 5.88%
Ill-Defined Disorder: 1 person, 5.88%
Body Height Below Normal: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Cyclosporine and have Knee deformity?

- Check whether Knee deformity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cyclosporine:

Cyclosporine (58,714 reports)

Knee deformity treatments and more:

Knee deformity (1,878 reports)

Browse all side effects of Cyclosporine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Knee deformity:

Knee deformity (189 drugs)

Browse all the conditions that are associated with Knee deformity:

Knee deformity (107 conditions)

Related publications that referenced our studies

O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on cyclosporine (the active ingredients of Cyclosporine) and Cyclosporine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.