Cycrin and Joint pain - a phase IV clinical study of FDA data

Summary:

Joint pain is reported as a side effect among people who take Cycrin (medroxyprogesterone acetate), especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years also take Premarin, and have Menopause.

The phase IV clinical study analyzes which people have Joint pain when taking Cycrin. It is created by eHealthMe based on reports of 5,085 people who have side effects when taking Cycrin from the FDA, and is updated regularly.

What is Cycrin?

Cycrin has active ingredients of medroxyprogesterone acetate. eHealthMe is studying from 5,086 Cycrin users. Check the latest studies of Cycrin.

What is Joint pain?

Joint pain is found to be associated with 3,331 drugs and 5,204 conditions by eHealthMe. Check the latest studies of Joint pain.

On Jul, 13, 2026

5,085 people reported to have side effects when taking Cycrin.
Among them, 31 people (0.61%) have Joint pain.

Among these 31 people:

How long have people been on Cycrin when they have Joint pain? *

What is the gender of people who have Joint pain when taking Cycrin? *

female: 93.33 %
male: 6.67 %

What is the age of people who have Joint pain when taking Cycrin? *

What are other drugs people take besides Cycrin? *

Premarin: 24 people, 77.42%
Prempro: 22 people, 70.97%
Provera: 20 people, 64.52%
Estraderm: 18 people, 58.06%
Fosamax: 12 people, 38.71%
Medroxyprogesterone Acetate: 8 people, 25.81%
Prometrium: 7 people, 22.58%
Synthroid: 6 people, 19.35%
Progesterone: 5 people, 16.13%
Furosemide: 4 people, 12.90%

What are other side effects people have besides Joint pain? *

Depression: 13 people, 41.94%
Muscle Aches (muscle pain): 12 people, 38.71%
Back Pain: 12 people, 38.71%
Insomnia (sleeplessness): 11 people, 35.48%
Osteopenia (a condition where bone mineral density is lower than normal): 11 people, 35.48%
Hot Flush (sudden feelings of heat): 11 people, 35.48%
Osteoporosis (bones weak and more likely to break): 9 people, 29.03%
Breast Cancer: 9 people, 29.03%
Spinal Osteoarthritis (joint cartilage loss in spine): 8 people, 25.81%
Headache (pain in head): 8 people, 25.81%

What are the existing conditions these people have? *

Menopause (end of monthly cycles in women): 11 people, 35.48%
Osteoporosis (bones weak and more likely to break): 5 people, 16.13%
Menopausal Symptoms: 5 people, 16.13%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 12.90%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 3 people, 9.68%
Depression: 3 people, 9.68%
Migraine (headache): 3 people, 9.68%
High Blood Pressure: 2 people, 6.45%
Bone Density Decreased: 2 people, 6.45%
Diabetes: 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Cycrin and have Joint pain?

- Check whether Joint pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cycrin:

Cycrin (5,086 reports)

Joint pain treatments and more:

Joint pain (542,934 reports)

Browse all side effects of Cycrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint pain:

Joint pain (3,331 drugs)

Browse all the conditions that are associated with Joint pain:

Joint pain (5,204 conditions)

Related publications that referenced our studies

Bahall M, Reyes AJ, Ramcharan K, Hosein N, Seegobin K, Bahall K, Sharma H, Dhansingh S, Mahabir A, "Neuro-ophthalmological manifestations after intramuscular medroxyprogesterone: a forme fruste of idiopathic intracranial hypertension?", Neurology international, 2016 Sep .
Bahall M, Reyes AJ, Ramcharan K, Hosein N, Seegobin K, Bahall K, Sharma H, Dhansingh S, Mahabir A, "Neuro-ophthalmological manifestations after intramuscular medroxyprogesterone: a forme fruste of idiopathic intracranial hypertension?", Neurology international, 2016 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on medroxyprogesterone acetate (the active ingredients of Cycrin) and Cycrin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.